Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 18504
  • Symbol: Pax2
  • Description: paired box 2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18504 GO:0000122 IGI acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II 15905411 Process
18504 GO:0001655 IGI involved_in urogenital system development 12435636 Process
18504 GO:0001655 IMP acts_upstream_of_or_within urogenital system development 8575306 Process
18504 GO:0001656 IGI acts_upstream_of_or_within metanephros development 12435636 Process
18504 GO:0001656 IMP acts_upstream_of_or_within metanephros development 8575306 Process
18504 GO:0001657 IGI acts_upstream_of_or_within ureteric bud development 16018995 Process
18504 GO:0001658 IGI acts_upstream_of_or_within branching involved in ureteric bud morphogenesis 16672320 Process
18504 GO:0001658 IMP acts_upstream_of_or_within branching involved in ureteric bud morphogenesis 16672320 Process
18504 GO:0001709 IMP acts_upstream_of_or_within cell fate determination 12756174 Process
18504 GO:0001822 IGI acts_upstream_of_or_within kidney development 16672320 Process
18504 GO:0001822 IMP acts_upstream_of_or_within kidney development 16672320 Process
18504 GO:0001823 IMP acts_upstream_of_or_within mesonephros development 8575306 Process
18504 GO:0001823 IMP involved_in mesonephros development 12435636 Process
18504 GO:0001843 IMP involved_in neural tube closure 8951055 Process
18504 GO:0002072 IMP involved_in optic cup morphogenesis involved in camera-type eye development 8951055 Process
18504 GO:0003337 IEP involved_in mesenchymal to epithelial transition involved in metanephros morphogenesis 10322633 Process
18504 GO:0003406 IMP involved_in retinal pigment epithelium development 8951055 Process
18504 GO:0007417 IEP involved_in central nervous system development 1723950 Process
18504 GO:0007501 IDA involved_in mesodermal cell fate specification 17785448 Process
18504 GO:0010001 IMP involved_in glial cell differentiation 8951055 Process
18504 GO:0021554 IMP involved_in optic nerve development 8951055 Process
18504 GO:0021631 IMP involved_in optic nerve morphogenesis 8951055 Process
18504 GO:0021633 IMP involved_in optic nerve structural organization 8951055 Process
18504 GO:0021650 IMP involved_in vestibulocochlear nerve formation 8951055 Process
18504 GO:0031016 IEP involved_in pancreas development 1723950 Process
18504 GO:0035566 IMP involved_in regulation of metanephros size 17881463 Process
18504 GO:0035799 IMP involved_in ureter maturation 17881463 Process
18504 GO:0039003 IEP involved_in pronephric field specification 12435636 Process
18504 GO:0042472 IGI acts_upstream_of_or_within inner ear morphogenesis 16916509 Process
18504 GO:0042472 IGI involved_in inner ear morphogenesis 20727173 Process
18504 GO:0042472 IMP acts_upstream_of_or_within inner ear morphogenesis 15242798 Process
18504 GO:0042472 IMP involved_in inner ear morphogenesis 8951055 Process
18504 GO:0042981 IMP involved_in regulation of apoptotic process 12435636 Process
18504 GO:0043010 IMP acts_upstream_of_or_within camera-type eye development 12756174 Process
18504 GO:0043066 IMP involved_in negative regulation of apoptotic process 10980123,17164400 Process
18504 GO:0043067 IGI acts_upstream_of_or_within regulation of programmed cell death 16672320 Process
18504 GO:0043069 IMP acts_upstream_of_or_within negative regulation of programmed cell death 16672320 Process
18504 GO:0043491 IMP involved_in protein kinase B signaling 17538188 Process
18504 GO:0045893 IDA involved_in positive regulation of DNA-templated transcription 8413205,17047028,17785448,19037705 Process
18504 GO:0045893 IGI involved_in positive regulation of DNA-templated transcription 16319112 Process
18504 GO:0045893 IMP involved_in positive regulation of DNA-templated transcription 12435636,16368682,16735463,17166926,17314325 Process
18504 GO:0045944 IDA acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 12200151 Process
18504 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 11731455 Process
18504 GO:0048793 IMP involved_in pronephros development 12435636 Process
18504 GO:0048854 IMP involved_in brain morphogenesis 8951055 Process
18504 GO:0048863 IDA involved_in stem cell differentiation 20171952 Process
18504 GO:0060231 IMP acts_upstream_of_or_within mesenchymal to epithelial transition 8575306 Process
18504 GO:0061205 IMP involved_in paramesonephric duct development 14695376 Process
18504 GO:0061360 IMP involved_in optic chiasma development 8951055 Process
18504 GO:0070301 IEP involved_in cellular response to hydrogen peroxide 17538188 Process
18504 GO:0071260 IEP involved_in cellular response to mechanical stimulus 17164400 Process
18504 GO:0071300 IEP involved_in cellular response to retinoic acid 20171952 Process
18504 GO:0071333 IEP involved_in cellular response to glucose stimulus 17538188 Process
18504 GO:0071333 IMP involved_in cellular response to glucose stimulus 17357786 Process
18504 GO:0072075 IDA involved_in metanephric mesenchyme development 20171952 Process
18504 GO:0072108 IGI involved_in positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 12435636 Process
18504 GO:0072162 IMP involved_in metanephric mesenchymal cell differentiation 16368682 Process
18504 GO:0072164 IEP involved_in mesonephric tubule development 1723950 Process
18504 GO:0072164 IMP involved_in mesonephric tubule development 14695376 Process
18504 GO:0072172 IMP involved_in mesonephric tubule formation 17300925 Process
18504 GO:0072177 IEP involved_in mesonephric duct development 1723950 Process
18504 GO:0072177 IMP involved_in mesonephric duct development 14695376 Process
18504 GO:0072179 IDA involved_in nephric duct formation 12435636 Process
18504 GO:0072189 IMP involved_in ureter development 17881463 Process
18504 GO:0072197 IEP involved_in ureter morphogenesis 1723950 Process
18504 GO:0072197 IGI acts_upstream_of_or_within ureter morphogenesis 21731775 Process
18504 GO:0072205 IMP involved_in metanephric collecting duct development 10980123 Process
18504 GO:0072207 IEP involved_in metanephric epithelium development 7856737 Process
18504 GO:0072221 IMP involved_in metanephric distal convoluted tubule development 17314325 Process
18504 GO:0072289 IMP involved_in metanephric nephron tubule formation 17314325 Process
18504 GO:0072300 IMP involved_in positive regulation of metanephric glomerulus development 17047028 Process
18504 GO:0072305 IMP involved_in negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis 17314325 Process
18504 GO:0072307 IMP involved_in regulation of metanephric nephron tubule epithelial cell differentiation 17314325 Process
18504 GO:0072593 IMP involved_in reactive oxygen species metabolic process 17538188 Process
18504 GO:0090102 IMP involved_in cochlea development 8951055 Process
18504 GO:0090103 IGI involved_in cochlea morphogenesis 20727173 Process
18504 GO:0090103 IMP acts_upstream_of_or_within cochlea morphogenesis 16916509 Process
18504 GO:0090103 IMP involved_in cochlea morphogenesis 8951055 Process
18504 GO:0090190 IMP involved_in positive regulation of branching involved in ureteric bud morphogenesis 17314325,17538188,17881463 Process
18504 GO:1900212 IMP involved_in negative regulation of mesenchymal cell apoptotic process involved in metanephros development 17314325 Process
18504 GO:1900215 IMP involved_in negative regulation of apoptotic process involved in metanephric collecting duct development 17314325 Process
18504 GO:1900218 IMP involved_in negative regulation of apoptotic process involved in metanephric nephron tubule development 17314325 Process
18504 GO:2000594 IMP involved_in positive regulation of metanephric DCT cell differentiation 17314325 Process
18504 GO:2000597 IMP involved_in positive regulation of optic nerve formation 18083586 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18504 GO:0000976 IDA enables transcription cis-regulatory region binding 17047028 Function
18504 GO:0000978 IDA enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 11731455 Function
18504 GO:0000981 IDA enables DNA-binding transcription factor activity, RNA polymerase II-specific 11731455 Function
18504 GO:0000987 IDA enables cis-regulatory region sequence-specific DNA binding 17785448 Function
18504 GO:0003677 IDA enables DNA binding 12756174 Function
18504 GO:0005515 IPI enables protein binding 10908331,12200151 Function
18504 GO:0070742 IPI enables C2H2 zinc finger domain binding 7720589 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18504 GO:0005634 IDA located_in nucleus 10536059,15153556,18607644 Component
18504 GO:0032991 IDA part_of protein-containing complex 17785448 Component
18504 GO:0032993 IDA part_of protein-DNA complex 17785448 Component