Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 1859
  • Symbol: DYRK1A
  • Description: dual specificity tyrosine phosphorylation regulated kinase 1A

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1859 GO:0004674 IGI enables protein serine/threonine kinase activity 17906291,25556849 Function
1859 GO:0004715 IDA enables non-membrane spanning protein tyrosine kinase activity 9748265 Function
1859 GO:0005515 IPI enables protein binding 14500717,14593110,15694837,20736167,20940704,23602568,26949739..... Function
1859 GO:0008353 IDA enables RNA polymerase II CTD heptapeptide repeat kinase activity 25620562,29849146 Function
1859 GO:0106310 IDA enables protein serine kinase activity 30773093 Function
1859 GO:0140857 IDA enables histone H3T45 kinase activity 24820035 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1859 GO:0005634 IDA is_active_in nucleus 25620562 Component
1859 GO:0005634 IDA located_in nucleus 15694837,23415227 Component
1859 GO:0005737 IDA located_in cytoplasm 15694837 Component
1859 GO:0005856 IDA colocalizes_with cytoskeleton 24327345 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1859 GO:0018105 IGI involved_in peptidyl-serine phosphorylation 25556849 Process
1859 GO:0018108 IDA acts_upstream_of_or_within peptidyl-tyrosine phosphorylation 9748265 Process
1859 GO:0033120 IDA involved_in positive regulation of RNA splicing 28377597 Process
1859 GO:0034205 IMP involved_in amyloid-beta formation 25556849 Process
1859 GO:0038083 IDA involved_in peptidyl-tyrosine autophosphorylation 24327345 Process
1859 GO:0090310 IDA involved_in negative regulation of DNA methylation-dependent heterochromatin formation 24820035 Process