Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 18706
  • Symbol: Pik3ca
  • Description: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18706 GO:0001889 IMP acts_upstream_of_or_within liver development 24691033 Process
18706 GO:0001932 IDA acts_upstream_of_or_within regulation of protein phosphorylation 15192701 Process
18706 GO:0006006 IMP acts_upstream_of_or_within glucose metabolic process 16625210 Process
18706 GO:0008286 IMP involved_in insulin receptor signaling pathway 20197055 Process
18706 GO:0010468 IMP acts_upstream_of_or_within regulation of gene expression 17475835 Process
18706 GO:0014065 IMP involved_in phosphatidylinositol 3-kinase signaling 30568254 Process
18706 GO:0030036 IMP involved_in actin cytoskeleton organization 30568254 Process
18706 GO:0030835 IMP involved_in negative regulation of actin filament depolymerization 30568254 Process
18706 GO:0033138 IDA involved_in positive regulation of peptidyl-serine phosphorylation 21047779 Process
18706 GO:0035994 IMP involved_in response to muscle stretch 30568254 Process
18706 GO:0040014 IMP acts_upstream_of_or_within regulation of multicellular organism growth 16625210 Process
18706 GO:0043457 IMP acts_upstream_of_or_within regulation of cellular respiration 24691033 Process
18706 GO:0043491 IMP acts_upstream_of_or_within protein kinase B signaling 16625210 Process
18706 GO:0043524 IMP acts_upstream_of_or_within negative regulation of neuron apoptotic process 12904469 Process
18706 GO:0044029 IDA involved_in positive regulation of gene expression via CpG island demethylation 21047779 Process
18706 GO:0048009 IDA involved_in insulin-like growth factor receptor signaling pathway 11784871 Process
18706 GO:0048009 IMP involved_in insulin-like growth factor receptor signaling pathway 26872540 Process
18706 GO:0055119 IMP involved_in relaxation of cardiac muscle 30568254 Process
18706 GO:0060612 IMP acts_upstream_of_or_within adipose tissue development 24691033 Process
18706 GO:0071333 IMP acts_upstream_of_or_within cellular response to glucose stimulus 24691033 Process
18706 GO:0071464 IMP involved_in cellular response to hydrostatic pressure 30568254 Process
18706 GO:0071514 IDA involved_in genomic imprinting 21047779 Process
18706 GO:0086003 IMP involved_in cardiac muscle cell contraction 30568254 Process
18706 GO:0097009 IMP acts_upstream_of_or_within energy homeostasis 24691033 Process
18706 GO:0110053 IMP involved_in regulation of actin filament organization 30568254 Process
18706 GO:2000270 IDA acts_upstream_of_or_within negative regulation of fibroblast apoptotic process 15192701 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18706 GO:0005515 IPI enables protein binding 7542745,15102471,17540175,18449193,27474268,30568254..... Function
18706 GO:0016303 IDA enables 1-phosphatidylinositol-3-kinase activity 11784871,14657280 Function
18706 GO:0016303 IMP enables 1-phosphatidylinositol-3-kinase activity 20197055,26872540 Function
18706 GO:0030295 IDA enables protein kinase activator activity 21047779 Function
18706 GO:0043560 IPI enables insulin receptor substrate binding 12486171 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18706 GO:0005942 IPI part_of phosphatidylinositol 3-kinase complex 7542745 Component
18706 GO:0014704 IDA located_in intercalated disc 30568254 Component
18706 GO:0030027 IDA located_in lamellipodium 14657280 Component