Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 18764
  • Symbol: Pkd2
  • Description: polycystin 2, transient receptor potential cation channel

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18764 GO:0001822 IGI acts_upstream_of_or_within kidney development 21685914 Process
18764 GO:0001822 IMP acts_upstream_of_or_within kidney development 10615132 Process
18764 GO:0001889 IGI acts_upstream_of_or_within liver development 21685914 Process
18764 GO:0001892 IMP acts_upstream_of_or_within embryonic placenta development 16301212 Process
18764 GO:0001892 IMP involved_in embryonic placenta development 20862291 Process
18764 GO:0003127 IMP involved_in detection of nodal flow 21307093 Process
18764 GO:0006816 IDA involved_in calcium ion transport 12514735 Process
18764 GO:0006816 IMP acts_upstream_of_or_within calcium ion transport 12514735 Process
18764 GO:0006874 IMP acts_upstream_of_or_within intracellular calcium ion homeostasis 12874107 Process
18764 GO:0007259 EXP involved_in receptor signaling pathway via JAK-STAT 12007403 Process
18764 GO:0007259 IDA acts_upstream_of_or_within receptor signaling pathway via JAK-STAT 12007403 Process
18764 GO:0007368 IMP acts_upstream_of_or_within determination of left/right symmetry 12062060 Process
18764 GO:0007507 IMP acts_upstream_of_or_within heart development 10615132 Process
18764 GO:0010628 IMP involved_in positive regulation of gene expression 20181743 Process
18764 GO:0045429 IMP involved_in positive regulation of nitric oxide biosynthetic process 19265036 Process
18764 GO:0050982 IMP acts_upstream_of_or_within detection of mechanical stimulus 12514735 Process
18764 GO:0051209 IMP acts_upstream_of_or_within release of sequestered calcium ion into cytosol 17404231 Process
18764 GO:0051209 IMP involved_in release of sequestered calcium ion into cytosol 19265036 Process
18764 GO:0051649 IMP acts_upstream_of_or_within establishment of localization in cell 12514735,17404231 Process
18764 GO:0051726 IDA acts_upstream_of_or_within regulation of cell cycle 12007403 Process
18764 GO:0060315 IDA acts_upstream_of_or_within negative regulation of ryanodine-sensitive calcium-release channel activity 17404231 Process
18764 GO:0060674 IMP involved_in placenta blood vessel development 20862291 Process
18764 GO:0061333 IMP involved_in renal tubule morphogenesis 20181743 Process
18764 GO:0070588 IMP involved_in calcium ion transmembrane transport 27760766 Process
18764 GO:0071277 IMP involved_in cellular response to calcium ion 27760766 Process
18764 GO:0071498 IMP involved_in cellular response to fluid shear stress 19265036 Process
18764 GO:0071805 IMP involved_in potassium ion transmembrane transport 27760766 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18764 GO:0002133 IDA part_of polycystin complex 11901144,25405894 Component
18764 GO:0002133 IPI part_of polycystin complex 11901144 Component
18764 GO:0005737 IDA located_in cytoplasm 10770959 Component
18764 GO:0005783 IDA located_in endoplasmic reticulum 16192288,25405894 Component
18764 GO:0005783 IMP located_in endoplasmic reticulum 12640140 Component
18764 GO:0005794 IDA located_in Golgi apparatus 25405894 Component
18764 GO:0005886 IDA located_in plasma membrane 12640140 Component
18764 GO:0005911 IDA colocalizes_with cell-cell junction 15843396 Component
18764 GO:0005929 IDA located_in cilium 12514735,12640140,16316413,18552856,19265036,21685914,25405894..... Component
18764 GO:0005929 IMP located_in cilium 21307093 Component
18764 GO:0031514 IDA located_in motile cilium 15858826 Component
18764 GO:0036064 IDA located_in ciliary basal body 22031837 Component
18764 GO:0045180 IDA located_in basal cortex 10770959 Component
18764 GO:0060170 IMP located_in ciliary membrane 27760766 Component
18764 GO:0072686 IDA located_in mitotic spindle 15123714 Component
18764 GO:0097730 IDA located_in non-motile cilium 12062067 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18764 GO:0005102 IPI enables signaling receptor binding 17404231 Function
18764 GO:0005262 IDA enables calcium channel activity 12640140 Function
18764 GO:0005262 IMP enables calcium channel activity 27760766 Function
18764 GO:0005267 IDA enables potassium channel activity 12640140 Function
18764 GO:0005509 IDA enables calcium ion binding 20408813 Function
18764 GO:0005515 IPI enables protein binding 10913159,11901144,12007403,15607428,18235088,18235101,21307093..... Function
18764 GO:0015267 IMP enables channel activity 18235088 Function
18764 GO:0015271 IMP enables outward rectifier potassium channel activity 27760766 Function
18764 GO:0042802 IPI enables identical protein binding 20408813 Function
18764 GO:0051117 IPI enables ATPase binding 18178578 Function