Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 18821
  • Symbol: Pln
  • Description: phospholamban

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18821 GO:0001675 IDA involved_in acrosome assembly 30733280 Process
18821 GO:0002026 IGI acts_upstream_of_or_within regulation of the force of heart contraction 10555147 Process
18821 GO:0002026 IMP acts_upstream_of_or_within regulation of the force of heart contraction 9118481 Process
18821 GO:0006874 IDA involved_in intracellular calcium ion homeostasis 30733280 Process
18821 GO:0006874 IGI acts_upstream_of_or_within intracellular calcium ion homeostasis 10555147 Process
18821 GO:0007219 IDA acts_upstream_of_or_within Notch signaling pathway 23117660 Process
18821 GO:0008016 IMP acts_upstream_of_or_within regulation of heart contraction 8831698 Process
18821 GO:0010880 IMP acts_upstream_of_or_within regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 9118481 Process
18821 GO:0010881 IMP acts_upstream_of_or_within regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 8831698 Process
18821 GO:0045822 IGI acts_upstream_of_or_within negative regulation of heart contraction 10555147 Process
18821 GO:0045822 IMP acts_upstream_of_or_within negative regulation of heart contraction 8062415 Process
18821 GO:0046716 IGI acts_upstream_of_or_within muscle cell cellular homeostasis 10555147 Process
18821 GO:0048738 IGI acts_upstream_of_or_within cardiac muscle tissue development 10555147 Process
18821 GO:0060314 IMP acts_upstream_of_or_within regulation of ryanodine-sensitive calcium-release channel activity 10603936 Process
18821 GO:0086004 IMP acts_upstream_of_or_within regulation of cardiac muscle cell contraction 8620604 Process
18821 GO:0086023 IMP acts_upstream_of_or_within adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process 10471356 Process
18821 GO:0086092 IMP acts_upstream_of_or_within regulation of the force of heart contraction by cardiac conduction 10644605 Process
18821 GO:0090279 IMP acts_upstream_of_or_within regulation of calcium ion import 8620604 Process
18821 GO:1901077 IMP acts_upstream_of_or_within regulation of relaxation of muscle 10024311 Process
18821 GO:1901877 IDA acts_upstream_of_or_within negative regulation of calcium ion binding 27923914 Process
18821 GO:1901895 IDA acts_upstream_of_or_within negative regulation of ATPase-coupled calcium transmembrane transporter activity 27923914 Process
18821 GO:1901895 IMP involved_in negative regulation of ATPase-coupled calcium transmembrane transporter activity 30299255 Process
18821 GO:1902081 IMP involved_in negative regulation of calcium ion import into sarcoplasmic reticulum 30299255 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18821 GO:0005515 IPI enables protein binding 15201433,26644582,27923914,30299255,32873725 Function
18821 GO:0042803 IDA enables protein homodimerization activity 30299255 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
18821 GO:0005789 IDA located_in endoplasmic reticulum membrane 27923914,30733280 Component
18821 GO:0016529 IDA located_in sarcoplasmic reticulum 9038922 Component
18821 GO:0033017 IDA located_in sarcoplasmic reticulum membrane 26816378 Component