Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 19055
  • Symbol: Ppp3ca
  • Description: protein phosphatase 3, catalytic subunit, alpha isoform

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19055 GO:0000082 IMP acts_upstream_of_or_within G1/S transition of mitotic cell cycle 12660151 Process
19055 GO:0006470 IDA involved_in protein dephosphorylation 26794871 Process
19055 GO:0006470 IMP acts_upstream_of_or_within protein dephosphorylation 19560418,31637311 Process
19055 GO:0006606 IDA acts_upstream_of_or_within protein import into nucleus 11782539 Process
19055 GO:0006606 IMP acts_upstream_of_or_within protein import into nucleus 31637311 Process
19055 GO:0006816 IMP acts_upstream_of_or_within calcium ion transport 12660151 Process
19055 GO:0008544 IMP involved_in epidermis development 19626032 Process
19055 GO:0010613 IGI involved_in positive regulation of cardiac muscle hypertrophy 24161931,24657879 Process
19055 GO:0010628 IDA involved_in positive regulation of gene expression 24161931 Process
19055 GO:0010629 IDA involved_in negative regulation of gene expression 24161931 Process
19055 GO:0014883 IDA acts_upstream_of_or_within transition between fast and slow fiber 21427212 Process
19055 GO:0014898 IGI acts_upstream_of_or_within cardiac muscle hypertrophy in response to stress 12370307 Process
19055 GO:0016311 IDA acts_upstream_of_or_within dephosphorylation 12574411,16024798 Process
19055 GO:0019722 IGI acts_upstream_of_or_within calcium-mediated signaling 19560418 Process
19055 GO:0023057 IMP involved_in negative regulation of signaling 26029823 Process
19055 GO:0030216 IMP involved_in keratinocyte differentiation 19626032 Process
19055 GO:0033173 IDA acts_upstream_of_or_within calcineurin-NFAT signaling cascade 9017603,19188439,21427212 Process
19055 GO:0033173 IGI acts_upstream_of_or_within calcineurin-NFAT signaling cascade 18676376 Process
19055 GO:0033173 IMP acts_upstream_of_or_within calcineurin-NFAT signaling cascade 9515963,9515964 Process
19055 GO:0033555 IDA acts_upstream_of_or_within multicellular organismal response to stress 11782539 Process
19055 GO:0035562 IMP acts_upstream_of_or_within negative regulation of chromatin binding 23407945 Process
19055 GO:0042104 IMP involved_in positive regulation of activated T cell proliferation 8627154 Process
19055 GO:0045669 IMP involved_in positive regulation of osteoblast differentiation 16286645 Process
19055 GO:0045672 IMP involved_in positive regulation of osteoclast differentiation 16968888 Process
19055 GO:0045807 IMP involved_in positive regulation of endocytosis 20032460 Process
19055 GO:0045944 IDA acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 12808150 Process
19055 GO:0045944 IGI acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 17229811 Process
19055 GO:0045944 IGI involved_in positive regulation of transcription by RNA polymerase II 24161931 Process
19055 GO:0046878 IMP involved_in positive regulation of saliva secretion 21435446 Process
19055 GO:0048741 IMP acts_upstream_of_or_within skeletal muscle fiber development 16024798 Process
19055 GO:0048741 IMP involved_in skeletal muscle fiber development 12773574 Process
19055 GO:0048813 IMP acts_upstream_of dendrite morphogenesis 23407945 Process
19055 GO:0050774 IMP acts_upstream_of_or_within negative regulation of dendrite morphogenesis 23407945 Process
19055 GO:0050804 IMP acts_upstream_of_or_within modulation of chemical synaptic transmission 15590926 Process
19055 GO:0050804 IMP involved_in modulation of chemical synaptic transmission 10200317 Process
19055 GO:0051091 IDA acts_upstream_of_or_within positive regulation of DNA-binding transcription factor activity 23261540 Process
19055 GO:0060079 IGI acts_upstream_of_or_within excitatory postsynaptic potential 17428973 Process
19055 GO:0061006 IMP involved_in regulation of cell proliferation involved in kidney morphogenesis 15509543 Process
19055 GO:0090193 IMP involved_in positive regulation of glomerulus development 15509543 Process
19055 GO:0097205 IMP involved_in renal filtration 16735444 Process
19055 GO:0099170 IDA involved_in postsynaptic modulation of chemical synaptic transmission 11257222 Process
19055 GO:0099170 IMP involved_in postsynaptic modulation of chemical synaptic transmission 11257222 Process
19055 GO:1903244 IDA involved_in positive regulation of cardiac muscle hypertrophy in response to stress 19287093 Process
19055 GO:1905205 IGI involved_in positive regulation of connective tissue replacement 24657879 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19055 GO:0004721 IDA enables phosphoprotein phosphatase activity 16024798 Function
19055 GO:0005515 IPI enables protein binding 12574411,12617961,12809556,15665106,16717086,18639592,19560418..... Function
19055 GO:0005516 IDA enables calmodulin binding 26794871 Function
19055 GO:0033192 IDA enables calmodulin-dependent protein phosphatase activity 26794871 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19055 GO:0005634 IDA located_in nucleus 12617961 Component
19055 GO:0005737 IDA located_in cytoplasm 16286645,16968888 Component
19055 GO:0005739 IDA located_in mitochondrion 12617961 Component
19055 GO:0005829 IDA located_in cytosol 12617961 Component
19055 GO:0005955 IDA part_of calcineurin complex 12617961,26794871 Component
19055 GO:0030018 IDA located_in Z disc 15665106 Component
19055 GO:0098685 IDA is_active_in Schaffer collateral - CA1 synapse 11257222 Component
19055 GO:0098685 IMP is_active_in Schaffer collateral - CA1 synapse 11257222 Component
19055 GO:0098794 IDA located_in postsynapse 11257222 Component
19055 GO:0098978 IDA is_active_in glutamatergic synapse 11257222 Component
19055 GO:0098978 IMP is_active_in glutamatergic synapse 11257222 Component