Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 19211
  • Symbol: Pten
  • Description: phosphatase and tensin homolog

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19211 GO:0001525 IMP acts_upstream_of_or_within angiogenesis 16107612 Process
19211 GO:0001933 IMP involved_in negative regulation of protein phosphorylation 19147652 Process
19211 GO:0002902 IMP acts_upstream_of_or_within regulation of B cell apoptotic process 9990064 Process
19211 GO:0007270 IMP involved_in neuron-neuron synaptic transmission 18082964 Process
19211 GO:0007416 IMP involved_in synapse assembly 16675393 Process
19211 GO:0007417 IMP acts_upstream_of_or_within central nervous system development 12091320 Process
19211 GO:0007507 IMP acts_upstream_of_or_within heart development 15755804 Process
19211 GO:0007611 IMP involved_in learning or memory 16675393 Process
19211 GO:0007626 IMP involved_in locomotory behavior 16675393 Process
19211 GO:0008283 IGI acts_upstream_of cell population proliferation 16027168 Process
19211 GO:0008283 IMP acts_upstream_of cell population proliferation 16027169 Process
19211 GO:0008284 IMP involved_in positive regulation of cell population proliferation 21241890 Process
19211 GO:0008285 IGI acts_upstream_of_or_within negative regulation of cell population proliferation 16027168 Process
19211 GO:0010975 IMP involved_in regulation of neuron projection development 19778506 Process
19211 GO:0016477 IMP acts_upstream_of_or_within cell migration 12091320 Process
19211 GO:0021542 IMP involved_in dentate gyrus development 17706614 Process
19211 GO:0021955 IMP involved_in central nervous system neuron axonogenesis 16675393 Process
19211 GO:0030534 IMP involved_in adult behavior 16675393 Process
19211 GO:0030889 IMP acts_upstream_of_or_within negative regulation of B cell proliferation 16027169 Process
19211 GO:0031642 IMP acts_upstream_of_or_within negative regulation of myelination 20448149 Process
19211 GO:0032228 IMP acts_upstream_of_or_within regulation of synaptic transmission, GABAergic 24875179 Process
19211 GO:0032286 IMP involved_in central nervous system myelin maintenance 18082964 Process
19211 GO:0032535 IMP involved_in regulation of cellular component size 18082964 Process
19211 GO:0033555 IMP involved_in multicellular organismal response to stress 16675393 Process
19211 GO:0035176 IMP involved_in social behavior 16675393,19208814 Process
19211 GO:0036294 IDA acts_upstream_of_or_within cellular response to decreased oxygen levels 24875179 Process
19211 GO:0042098 IMP acts_upstream_of T cell proliferation 16027169 Process
19211 GO:0042100 IMP acts_upstream_of B cell proliferation 16027169 Process
19211 GO:0042130 IMP acts_upstream_of_or_within negative regulation of T cell proliferation 16027169 Process
19211 GO:0042552 IMP acts_upstream_of myelination 20448149 Process
19211 GO:0042711 IMP involved_in maternal behavior 16675393 Process
19211 GO:0043066 IMP involved_in negative regulation of apoptotic process 10339565 Process
19211 GO:0043491 IMP acts_upstream_of protein kinase B signaling 20448149,25512490 Process
19211 GO:0043491 IMP involved_in protein kinase B signaling 19147652,20940307 Process
19211 GO:0043542 IMP acts_upstream_of_or_within endothelial cell migration 16107612 Process
19211 GO:0045475 IMP involved_in locomotor rhythm 17706614 Process
19211 GO:0045792 IMP involved_in negative regulation of cell size 16675393,21411674 Process
19211 GO:0046621 IMP involved_in negative regulation of organ growth 19208814 Process
19211 GO:0048679 IGI acts_upstream_of_or_within regulation of axon regeneration 24733831 Process
19211 GO:0048681 IMP involved_in negative regulation of axon regeneration 26203138 Process
19211 GO:0048738 IMP acts_upstream_of_or_within cardiac muscle tissue development 16107612 Process
19211 GO:0048853 IMP involved_in forebrain morphogenesis 16675393 Process
19211 GO:0048854 IMP involved_in brain morphogenesis 19208814 Process
19211 GO:0050680 IMP acts_upstream_of_or_within negative regulation of epithelial cell proliferation 15994948 Process
19211 GO:0050771 IMP involved_in negative regulation of axonogenesis 16675393 Process
19211 GO:0051726 IGI acts_upstream_of_or_within regulation of cell cycle 18332125 Process
19211 GO:0051898 IMP acts_upstream_of_or_within negative regulation of protein kinase B signaling 20448149,25512490 Process
19211 GO:0051898 IMP involved_in negative regulation of protein kinase B signaling 10339565,16675393 Process
19211 GO:0060024 IMP involved_in rhythmic synaptic transmission 17706614 Process
19211 GO:0060044 IGI involved_in negative regulation of cardiac muscle cell proliferation 23575307 Process
19211 GO:0060074 IMP involved_in synapse maturation 18082964 Process
19211 GO:0060134 IMP involved_in prepulse inhibition 16675393,19208814 Process
19211 GO:0060179 IMP involved_in male mating behavior 16675393 Process
19211 GO:0060291 IMP involved_in long-term synaptic potentiation 18082964 Process
19211 GO:0060341 IMP involved_in regulation of cellular localization 21266327 Process
19211 GO:0060736 IMP acts_upstream_of_or_within prostate gland growth 15994948 Process
19211 GO:0060997 IMP involved_in dendritic spine morphogenesis 18082964,21411674 Process
19211 GO:0061002 IMP involved_in negative regulation of dendritic spine morphogenesis 16675393 Process
19211 GO:0070374 IMP acts_upstream_of_or_within positive regulation of ERK1 and ERK2 cascade 25512490 Process
19211 GO:0071456 IDA acts_upstream_of_or_within cellular response to hypoxia 24875179 Process
19211 GO:0090071 IMP involved_in negative regulation of ribosome biogenesis 18082964 Process
19211 GO:0090394 IMP involved_in negative regulation of excitatory postsynaptic potential 21411674 Process
19211 GO:0097105 IMP involved_in presynaptic membrane assembly 18082964 Process
19211 GO:0097107 IMP involved_in postsynaptic density assembly 18082964 Process
19211 GO:1904668 IMP involved_in positive regulation of ubiquitin protein ligase activity 21241890 Process
19211 GO:2000109 IMP acts_upstream_of_or_within regulation of macrophage apoptotic process 9990064 Process
19211 GO:2000463 IMP involved_in positive regulation of excitatory postsynaptic potential 18082964 Process
19211 GO:2000773 IMP involved_in negative regulation of cellular senescence 21241890 Process
19211 GO:2000808 IMP involved_in negative regulation of synaptic vesicle clustering 16675393,18082964 Process
19211 GO:2001235 IMP acts_upstream_of_or_within positive regulation of apoptotic signaling pathway 9778245 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19211 GO:0005515 IPI enables protein binding 16456542,17218262,18190691,18332125,18716620,20448149,23123091..... Function
19211 GO:0016314 IDA enables phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity 9778245 Function
19211 GO:0019901 IPI enables protein kinase binding 20940307 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19211 GO:0005634 IDA located_in nucleus 14522255,18332125,18562292 Component
19211 GO:0005737 IDA located_in cytoplasm 14522255,18562292 Component
19211 GO:0035749 IDA located_in myelin sheath adaxonal region 20237282 Component
19211 GO:0043005 IDA located_in neuron projection 21664258 Component
19211 GO:0043005 IMP located_in neuron projection 21664258 Component
19211 GO:0043220 IDA located_in Schmidt-Lanterman incisure 20237282 Component