Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 19246
  • Symbol: Ptpn1
  • Description: protein tyrosine phosphatase, non-receptor type 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19246 GO:0004725 IDA enables protein tyrosine phosphatase activity 15632081 Function
19246 GO:0004725 IMP enables protein tyrosine phosphatase activity 17068137 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19246 GO:0005737 IDA located_in cytoplasm 21216966 Component
19246 GO:0005769 IDA located_in early endosome 23639442 Component
19246 GO:0031904 IDA is_active_in endosome lumen 23639442 Component
19246 GO:0097443 IDA located_in sorting endosome 23639442 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19246 GO:0006470 IMP acts_upstream_of_or_within protein dephosphorylation 15632081 Process
19246 GO:0008286 IMP acts_upstream_of_or_within insulin receptor signaling pathway 15632081 Process
19246 GO:0030948 IGI involved_in negative regulation of vascular endothelial growth factor receptor signaling pathway 23639442 Process
19246 GO:0034976 IMP involved_in response to endoplasmic reticulum stress 15465829 Process
19246 GO:0035335 IMP involved_in peptidyl-tyrosine dephosphorylation 14966296 Process
19246 GO:0035791 IMP involved_in platelet-derived growth factor receptor-beta signaling pathway 14966296 Process
19246 GO:0036498 IMP involved_in IRE1-mediated unfolded protein response 15465829 Process
19246 GO:0038020 IMP involved_in insulin receptor recycling 17068137 Process
19246 GO:0043507 IMP acts_upstream_of positive regulation of JUN kinase activity 15465829 Process
19246 GO:0070373 IGI involved_in negative regulation of ERK1 and ERK2 cascade 23639442 Process
19246 GO:1902236 IMP involved_in negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 21216966 Process
19246 GO:1903898 IMP involved_in negative regulation of PERK-mediated unfolded protein response 21216966 Process
19246 GO:1990264 IGI involved_in peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity 23639442 Process