Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 19247
  • Symbol: Ptpn11
  • Description: protein tyrosine phosphatase, non-receptor type 11

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19247 GO:0000077 IMP acts_upstream_of_or_within DNA damage checkpoint signaling 12937170 Process
19247 GO:0006629 IMP acts_upstream_of_or_within lipid metabolic process 15520383 Process
19247 GO:0006641 IMP acts_upstream_of_or_within triglyceride metabolic process 15520383 Process
19247 GO:0007165 IMP acts_upstream_of signal transduction 15520383 Process
19247 GO:0007173 IGI acts_upstream_of_or_within epidermal growth factor receptor signaling pathway 18827006 Process
19247 GO:0007173 IGI involved_in epidermal growth factor receptor signaling pathway 10700187 Process
19247 GO:0007229 IMP acts_upstream_of_or_within integrin-mediated signaling pathway 23509158 Process
19247 GO:0007409 IMP acts_upstream_of_or_within axonogenesis 12482708 Process
19247 GO:0009755 IDA acts_upstream_of_or_within hormone-mediated signaling pathway 15520383 Process
19247 GO:0009967 IMP acts_upstream_of_or_within positive regulation of signal transduction 15520383 Process
19247 GO:0021697 IGI acts_upstream_of_or_within cerebellar cortex formation 24431450 Process
19247 GO:0021697 IMP acts_upstream_of_or_within cerebellar cortex formation 24431450 Process
19247 GO:0030220 IGI acts_upstream_of_or_within platelet formation 23509158 Process
19247 GO:0032331 IMP involved_in negative regulation of chondrocyte differentiation 29644115 Process
19247 GO:0032528 IMP acts_upstream_of_or_within microvillus organization 24675817 Process
19247 GO:0032728 IMP involved_in positive regulation of interferon-beta production 17954568 Process
19247 GO:0032755 IGI involved_in positive regulation of interleukin-6 production 17954568 Process
19247 GO:0032760 IGI involved_in positive regulation of tumor necrosis factor production 17954568 Process
19247 GO:0033629 IMP acts_upstream_of_or_within negative regulation of cell adhesion mediated by integrin 23509158 Process
19247 GO:0035264 IMP acts_upstream_of_or_within multicellular organism growth 15520383,24675817 Process
19247 GO:0035265 IMP acts_upstream_of_or_within organ growth 15520383 Process
19247 GO:0035855 IMP acts_upstream_of_or_within megakaryocyte development 23509158 Process
19247 GO:0042445 IMP acts_upstream_of_or_within hormone metabolic process 15520383 Process
19247 GO:0042593 IMP acts_upstream_of_or_within glucose homeostasis 15520383 Process
19247 GO:0043408 IMP acts_upstream_of_or_within regulation of MAPK cascade 12937170,15273746 Process
19247 GO:0045778 IMP involved_in positive regulation of ossification 29644115 Process
19247 GO:0045931 IGI acts_upstream_of_or_within positive regulation of mitotic cell cycle 18827006 Process
19247 GO:0046676 IMP acts_upstream_of_or_within negative regulation of insulin secretion 15520383 Process
19247 GO:0046825 IMP acts_upstream_of_or_within regulation of protein export from nucleus 12937170 Process
19247 GO:0046887 IMP acts_upstream_of_or_within positive regulation of hormone secretion 15520383 Process
19247 GO:0046888 IMP acts_upstream_of_or_within negative regulation of hormone secretion 15520383 Process
19247 GO:0048008 IGI acts_upstream_of_or_within platelet-derived growth factor receptor signaling pathway 18827006 Process
19247 GO:0048011 IMP acts_upstream_of_or_within neurotrophin TRK receptor signaling pathway 12482708 Process
19247 GO:0048609 IMP acts_upstream_of_or_within multicellular organismal reproductive process 15520383 Process
19247 GO:0048873 IGI acts_upstream_of_or_within homeostasis of number of cells within a tissue 24675817 Process
19247 GO:0048873 IMP acts_upstream_of_or_within homeostasis of number of cells within a tissue 24675817 Process
19247 GO:0051463 IMP acts_upstream_of_or_within negative regulation of cortisol secretion 15520383 Process
19247 GO:0060020 IGI acts_upstream_of_or_within Bergmann glial cell differentiation 24431450 Process
19247 GO:0060020 IMP acts_upstream_of_or_within Bergmann glial cell differentiation 24431450 Process
19247 GO:0060125 IMP acts_upstream_of_or_within negative regulation of growth hormone secretion 15520383 Process
19247 GO:0061582 IMP acts_upstream_of_or_within intestinal epithelial cell migration 24675817 Process
19247 GO:0070374 IGI acts_upstream_of_or_within positive regulation of ERK1 and ERK2 cascade 18827006,24431450 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19247 GO:0004721 IMP enables phosphoprotein phosphatase activity 15273746 Function
19247 GO:0004725 IDA enables protein tyrosine phosphatase activity 18827006 Function
19247 GO:0004726 IMP enables non-membrane spanning protein tyrosine phosphatase activity 15273746 Function
19247 GO:0005515 IPI enables protein binding 7522233,7523381,8959326,9670943,9867848,10026201,11432792,1168..... Function
19247 GO:0019901 IPI enables protein kinase binding 17954568 Function
19247 GO:0030971 IPI enables receptor tyrosine kinase binding 16885344 Function
19247 GO:0050839 IPI enables cell adhesion molecule binding 19948503 Function
19247 GO:0051428 IPI enables peptide hormone receptor binding 15520383 Function