Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 19255
  • Symbol: Ptpn2
  • Description: protein tyrosine phosphatase, non-receptor type 2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19255 GO:0000122 IPI acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II 26026268 Process
19255 GO:0006470 IDA acts_upstream_of_or_within protein dephosphorylation 26026268 Process
19255 GO:0006470 IGI acts_upstream_of_or_within protein dephosphorylation 26026268 Process
19255 GO:0006470 IMP acts_upstream_of_or_within protein dephosphorylation 15632081 Process
19255 GO:0008286 IMP acts_upstream_of_or_within insulin receptor signaling pathway 15632081 Process
19255 GO:0010804 IMP involved_in negative regulation of tumor necrosis factor-mediated signaling pathway 15696169 Process
19255 GO:0010888 IMP involved_in negative regulation of lipid storage 20484139 Process
19255 GO:0030183 IMP involved_in B cell differentiation 9271584 Process
19255 GO:0030217 IMP involved_in T cell differentiation 9271584 Process
19255 GO:0030218 IMP involved_in erythrocyte differentiation 9271584 Process
19255 GO:0035335 IMP involved_in peptidyl-tyrosine dephosphorylation 14966296 Process
19255 GO:0038020 IDA involved_in insulin receptor recycling 15632081 Process
19255 GO:0042532 IMP involved_in negative regulation of tyrosine phosphorylation of STAT protein 17210636 Process
19255 GO:0042593 IMP involved_in glucose homeostasis 20484139 Process
19255 GO:0045650 IMP involved_in negative regulation of macrophage differentiation 16705167 Process
19255 GO:0045722 IMP involved_in positive regulation of gluconeogenesis 20484139 Process
19255 GO:0046627 IMP involved_in negative regulation of insulin receptor signaling pathway 12612081,20484139 Process
19255 GO:0050728 IMP involved_in negative regulation of inflammatory response 14726372 Process
19255 GO:0050860 IMP involved_in negative regulation of T cell receptor signaling pathway 22080863 Process
19255 GO:0050922 IMP involved_in negative regulation of chemotaxis 14966296 Process
19255 GO:0060336 IMP involved_in negative regulation of type II interferon-mediated signaling pathway 12138178 Process
19255 GO:0060339 IMP involved_in negative regulation of type I interferon-mediated signaling pathway 11909529,12138178 Process
19255 GO:0061099 IMP involved_in negative regulation of protein tyrosine kinase activity 21216966 Process
19255 GO:0070104 IMP involved_in negative regulation of interleukin-6-mediated signaling pathway 20484139 Process
19255 GO:0070373 IMP involved_in negative regulation of ERK1 and ERK2 cascade 15696169 Process
19255 GO:1902206 IMP involved_in negative regulation of interleukin-2-mediated signaling pathway 11909529 Process
19255 GO:1902215 IMP involved_in negative regulation of interleukin-4-mediated signaling pathway 17210636 Process
19255 GO:1902227 IMP involved_in negative regulation of macrophage colony-stimulating factor signaling pathway 16705167 Process
19255 GO:1902233 IMP involved_in negative regulation of positive thymic T cell selection 22080863 Process
19255 GO:1902237 IMP involved_in positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 21216966 Process
19255 GO:1903899 IMP involved_in positive regulation of PERK-mediated unfolded protein response 21216966 Process
19255 GO:2000587 IMP involved_in negative regulation of platelet-derived growth factor receptor-beta signaling pathway 14966296 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19255 GO:0004725 IDA enables protein tyrosine phosphatase activity 15632081 Function
19255 GO:0004725 IMP enables protein tyrosine phosphatase activity 14966296 Function
19255 GO:0005515 IPI enables protein binding 16705167,26026268 Function
19255 GO:0097677 IPI enables STAT family protein binding 26026268 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
19255 GO:0005634 IDA located_in nucleus 21216966,26026268 Component
19255 GO:0031904 IDA is_active_in endosome lumen 12612081 Component