Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 201163
  • Symbol: FLCN
  • Description: folliculin

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
201163 GO:0000122 IDA involved_in negative regulation of transcription by RNA polymerase II 20573232 Process
201163 GO:0000122 IMP involved_in negative regulation of transcription by RNA polymerase II 21209915 Process
201163 GO:0001932 IDA involved_in regulation of protein phosphorylation 18663353 Process
201163 GO:0009267 IDA involved_in cellular response to starvation 24095279,31672913 Process
201163 GO:0010508 IDA involved_in positive regulation of autophagy 25126726 Process
201163 GO:0010508 IMP involved_in positive regulation of autophagy 25126726 Process
201163 GO:0030308 IDA involved_in negative regulation of cell growth 20573232 Process
201163 GO:0030336 IMP involved_in negative regulation of cell migration 22965878 Process
201163 GO:0030511 IDA involved_in positive regulation of transforming growth factor beta receptor signaling pathway 20573232 Process
201163 GO:0031929 IMP involved_in TOR signaling 17028174 Process
201163 GO:0032008 IDA involved_in positive regulation of TOR signaling 24081491,24095279,31672913,31704029 Process
201163 GO:0032418 IDA involved_in lysosome localization 27113757 Process
201163 GO:0032465 IMP involved_in regulation of cytokinesis 22965878 Process
201163 GO:0034198 IDA involved_in cellular response to amino acid starvation 24095279,27113757,31672913 Process
201163 GO:0035024 IMP involved_in negative regulation of Rho protein signal transduction 22965878 Process
201163 GO:0045785 IMP involved_in positive regulation of cell adhesion 21209915 Process
201163 GO:0045820 IDA involved_in negative regulation of glycolytic process 34381247 Process
201163 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 20573232 Process
201163 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 21209915 Process
201163 GO:0046578 IDA involved_in regulation of Ras protein signal transduction 24081491,24095279,31672913,31704029 Process
201163 GO:1900181 IDA involved_in negative regulation of protein localization to nucleus 21209915 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
201163 GO:0004857 IDA enables enzyme inhibitor activity 34381247 Function
201163 GO:0005096 IDA enables GTPase activator activity 24095279,31672913,31704029 Function
201163 GO:0005515 IPI enables protein binding 17028174,18403135,18663353,22965878,25126726,27113757,27353360..... Function
201163 GO:0019899 IPI enables enzyme binding 34381247 Function
201163 GO:0044877 IDA enables protein-containing complex binding 17028174 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
201163 GO:0005634 IDA located_in nucleus 17028174,18663353 Component
201163 GO:0005737 IDA located_in cytoplasm 17028174,18663353,22965878 Component
201163 GO:0005765 IDA located_in lysosomal membrane 24081491,24095279,27113757,29848618,31672913 Component
201163 GO:0005813 IDA located_in centrosome 23784378 Component
201163 GO:0005829 IDA located_in cytosol 24081491,24095279,29848618,31672913 Component
201163 GO:0005886 IDA located_in plasma membrane Component
201163 GO:0005929 IDA located_in cilium 23784378 Component
201163 GO:0030496 IDA colocalizes_with midbody 22965878 Component
201163 GO:0044291 IDA colocalizes_with cell-cell contact zone 22965878 Component
201163 GO:0072686 IDA located_in mitotic spindle 23784378 Component