Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 2033
  • Symbol: EP300
  • Description: EP300 lysine acetyltransferase

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2033 GO:0000122 IDA involved_in negative regulation of transcription by RNA polymerase II 10733570 Process
2033 GO:0001666 IDA involved_in response to hypoxia 9887100,15261140 Process
2033 GO:0006110 IDA involved_in regulation of glycolytic process 29775581 Process
2033 GO:0006473 IDA involved_in protein acetylation 21030595,24939902 Process
2033 GO:0006475 IDA involved_in internal protein amino acid acetylation 18722353 Process
2033 GO:0006915 IMP involved_in apoptotic process 9194565 Process
2033 GO:0010742 IDA involved_in macrophage derived foam cell differentiation Process
2033 GO:0010976 IDA involved_in positive regulation of neuron projection development 27256286 Process
2033 GO:0018076 IDA involved_in N-terminal peptidyl-lysine acetylation 12435739 Process
2033 GO:0018393 IDA involved_in internal peptidyl-lysine acetylation 17403783 Process
2033 GO:0018394 IDA involved_in peptidyl-lysine acetylation 23811396,23962722 Process
2033 GO:0030511 IMP involved_in positive regulation of transforming growth factor beta receptor signaling pathway 25514493 Process
2033 GO:0031333 IDA involved_in negative regulation of protein-containing complex assembly 23962722 Process
2033 GO:0031648 IMP involved_in protein destabilization 24939902 Process
2033 GO:0034644 IDA involved_in cellular response to UV 24939902 Process
2033 GO:0042307 IDA involved_in positive regulation of protein import into nucleus 24120661 Process
2033 GO:0042771 IDA involved_in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 17403783 Process
2033 GO:0043627 IDA involved_in response to estrogen 11581164 Process
2033 GO:0043923 IDA involved_in positive regulation by host of viral transcription 16687403 Process
2033 GO:0045721 IDA involved_in negative regulation of gluconeogenesis 30193097 Process
2033 GO:0045815 IDA involved_in transcription initiation-coupled chromatin remodeling 25818647,27256286 Process
2033 GO:0045893 IDA involved_in positive regulation of DNA-templated transcription 15261140 Process
2033 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 12586840,18722353,23811396 Process
2033 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 16325578 Process
2033 GO:0046427 IDA involved_in positive regulation of receptor signaling pathway via JAK-STAT 16257975 Process
2033 GO:0051091 IDA involved_in positive regulation of DNA-binding transcription factor activity 10518217,25818647 Process
2033 GO:0051092 IDA involved_in positive regulation of NF-kappaB transcription factor activity 23811396 Process
2033 GO:0060765 IDA involved_in regulation of androgen receptor signaling pathway 18487222 Process
2033 GO:0061921 IDA involved_in peptidyl-lysine propionylation 17267393 Process
2033 GO:0090043 IDA involved_in regulation of tubulin deacetylation 18722353 Process
2033 GO:0140066 IDA involved_in peptidyl-lysine crotonylation 25818647 Process
2033 GO:0140067 IDA involved_in peptidyl-lysine butyrylation 17267393,29775581 Process
2033 GO:1901224 IDA involved_in positive regulation of NIK/NF-kappaB signaling 23811396 Process
2033 GO:1905636 IDA involved_in positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding 23811396 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2033 GO:0000785 IDA part_of chromatin 21084751 Component
2033 GO:0005634 IDA located_in nucleus 9194565,12929931,14645221,25593309 Component
2033 GO:0005654 IDA located_in nucleoplasm Component
2033 GO:0005737 IDA is_active_in cytoplasm 12929931 Component
2033 GO:0005829 IDA is_active_in cytosol 12929931 Component
2033 GO:0005829 IDA located_in cytosol Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2033 GO:0001221 IPI enables transcription coregulator binding 8684459 Function
2033 GO:0001223 IPI enables transcription coactivator binding 11349124 Function
2033 GO:0003677 IDA enables DNA binding 9194565 Function
2033 GO:0003682 IDA enables chromatin binding 24939902,25818647 Function
2033 GO:0003682 IMP enables chromatin binding 17641689 Function
2033 GO:0003684 IDA enables damaged DNA binding 24939902 Function
2033 GO:0003713 IDA enables transcription coactivator activity 12435739,12586840,12609999,12929931,15261140,16257975,16687403..... Function
2033 GO:0003713 IMP enables transcription coactivator activity 11349124,11940591 Function
2033 GO:0003713 IPI enables transcription coactivator activity 23811396 Function
2033 GO:0004402 IDA enables histone acetyltransferase activity 12040021,14645221,25818647 Function
2033 GO:0004468 IDA enables lysine N-acetyltransferase activity, acting on acetyl phosphate as donor 20019387 Function
2033 GO:0005515 IDA enables protein binding 17150957,26983400 Function
2033 GO:0005515 IPI enables protein binding 1331501,8684459,9018065,9194564,9194565,9811832,9881977,988710..... Function
2033 GO:0008013 IPI enables beta-catenin binding 12408825 Function
2033 GO:0010484 IDA enables histone H3 acetyltransferase activity 12609999,27256286 Function
2033 GO:0010485 IDA enables histone H4 acetyltransferase activity 10821277,12609999 Function
2033 GO:0010485 IMP enables histone H4 acetyltransferase activity 16325578 Function
2033 GO:0016407 EXP enables acetyltransferase activity 12456660,16135789,20228809 Function
2033 GO:0016407 IDA enables acetyltransferase activity 18722353,21084751,23811396,24939902 Function
2033 GO:0016407 IMP enables acetyltransferase activity 12435739 Function
2033 GO:0016746 IDA enables acyltransferase activity 17403783 Function
2033 GO:0016922 IPI enables nuclear receptor binding 9862959 Function
2033 GO:0044013 IDA enables histone H2B acetyltransferase activity 10821277 Function
2033 GO:0050681 IPI enables nuclear androgen receptor binding 18487222 Function
2033 GO:0051059 IPI enables NF-kappaB binding 23811396 Function
2033 GO:0061629 IPI enables RNA polymerase II-specific DNA-binding transcription factor binding 20018936,23329847,23811396 Function
2033 GO:0061733 IDA enables peptide-lysine-N-acetyltransferase activity 24120661,30193097 Function
2033 GO:0061920 IDA enables protein propionyltransferase activity 17267393 Function
2033 GO:0097677 IPI enables STAT family protein binding 26479788 Function
2033 GO:0120301 IDA enables histone lactyltransferase activity 31645732 Function
2033 GO:0140065 IDA enables peptide butyryltransferase activity 17267393,29775581 Function
2033 GO:0140068 IDA enables histone crotonyltransferase activity 25818647 Function
2033 GO:0140297 IPI enables DNA-binding transcription factor binding 15261140,15674325,20590529 Function
2033 GO:0140908 IDA enables histone H3K122 acetyltransferase activity 23415232 Function