Gene Ontology

Gene Info

• Species: Mouse (Mus musculus)
• GeneID: 20597
• Symbol: Smpd1
• Description: sphingomyelin phosphodiesterase 1, acid lysosomal

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
20597	GO:0001778	IDA	involved_in	plasma membrane repair	35705808	Process
20597	GO:0006672	IMP	acts_upstream_of_or_within	ceramide metabolic process	23046545	Process
20597	GO:0006685	IMP	acts_upstream_of_or_within	sphingomyelin catabolic process	23973266	Process
20597	GO:0008203	IMP	acts_upstream_of_or_within	cholesterol metabolic process	22383528	Process
20597	GO:0010212	IMP	involved_in	response to ionizing radiation	8706124	Process
20597	GO:0043065	IMP	involved_in	positive regulation of apoptotic process	8706124	Process
20597	GO:0046513	IDA	involved_in	ceramide biosynthetic process	35705808	Process
20597	GO:0046513	IMP	involved_in	ceramide biosynthetic process	8706124	Process

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
20597	GO:0005615	IDA	is_active_in	extracellular space	35705808	Component
20597	GO:0005615	IDA	located_in	extracellular space	8702487	Component

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
20597	GO:0008270	IDA	enables	zinc ion binding	8702487	Function
20597	GO:0061750	IDA	enables	acid sphingomyelin phosphodiesterase activity	8702487,16025116,23046545,35705808	Function