Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 20617
  • Symbol: Snca
  • Description: synuclein, alpha

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
20617 GO:0001774 IMP acts_upstream_of_or_within microglial cell activation 17035541 Process
20617 GO:0001956 IDA acts_upstream_of_or_within positive regulation of neurotransmitter secretion 15510220 Process
20617 GO:0001963 IMP acts_upstream_of_or_within synaptic transmission, dopaminergic 10707987,12388586 Process
20617 GO:0006631 IMP acts_upstream_of_or_within fatty acid metabolic process 14507911,17250686 Process
20617 GO:0006638 IMP acts_upstream_of_or_within neutral lipid metabolic process 17250686 Process
20617 GO:0006644 IMP acts_upstream_of_or_within phospholipid metabolic process 15938614,16260631,16734431 Process
20617 GO:0007006 IMP acts_upstream_of_or_within mitochondrial membrane organization 16260631 Process
20617 GO:0007268 IGI acts_upstream_of_or_within chemical synaptic transmission 20974939 Process
20617 GO:0007269 IDA acts_upstream_of neurotransmitter secretion 15510220 Process
20617 GO:0008344 IGI acts_upstream_of_or_within adult locomotory behavior 18333965 Process
20617 GO:0009410 IMP acts_upstream_of_or_within response to xenobiotic stimulus 10707987 Process
20617 GO:0014048 IMP acts_upstream_of_or_within regulation of glutamate secretion 17689254 Process
20617 GO:0014059 IGI acts_upstream_of_or_within regulation of dopamine secretion 18333965 Process
20617 GO:0033138 IMP involved_in positive regulation of peptidyl-serine phosphorylation 21127069 Process
20617 GO:0034599 IMP acts_upstream_of_or_within cellular response to oxidative stress 16298531 Process
20617 GO:0035493 IDA involved_in SNARE complex assembly 25246573 Process
20617 GO:0040012 IMP acts_upstream_of_or_within regulation of locomotion 10707987 Process
20617 GO:0042416 IMP acts_upstream_of_or_within dopamine biosynthetic process 10707987 Process
20617 GO:0042417 IGI acts_upstream_of_or_within dopamine metabolic process 15465911 Process
20617 GO:0042775 IMP acts_upstream_of_or_within mitochondrial ATP synthesis coupled electron transport 16260631 Process
20617 GO:0043030 IMP acts_upstream_of_or_within regulation of macrophage activation 17035541 Process
20617 GO:0043523 IMP NOT acts_upstream_of_or_within regulation of neuron apoptotic process 15380020 Process
20617 GO:0043524 IGI acts_upstream_of_or_within negative regulation of neuron apoptotic process 16269331 Process
20617 GO:0046928 IGI acts_upstream_of_or_within regulation of neurotransmitter secretion 18333965 Process
20617 GO:0046928 IMP acts_upstream_of_or_within regulation of neurotransmitter secretion 10707987,12388586,15510220 Process
20617 GO:0048168 IMP acts_upstream_of_or_within regulation of neuronal synaptic plasticity 17610578 Process
20617 GO:0048169 IMP acts_upstream_of_or_within regulation of long-term neuronal synaptic plasticity 15510220 Process
20617 GO:0048488 IDA involved_in synaptic vesicle endocytosis 25009269 Process
20617 GO:0048488 IMP involved_in synaptic vesicle endocytosis 18980610,25009269 Process
20617 GO:0048489 IMP acts_upstream_of_or_within synaptic vesicle transport 12388586 Process
20617 GO:0050806 IMP acts_upstream_of_or_within positive regulation of synaptic transmission 15579163 Process
20617 GO:0050808 IGI acts_upstream_of_or_within synapse organization 20974939 Process
20617 GO:0050812 IDA acts_upstream_of_or_within regulation of acyl-CoA biosynthetic process 16734431 Process
20617 GO:0050812 IMP acts_upstream_of_or_within regulation of acyl-CoA biosynthetic process 16636270 Process
20617 GO:0051259 IDA involved_in protein complex oligomerization 25246573 Process
20617 GO:0051402 IGI acts_upstream_of neuron apoptotic process 16269331 Process
20617 GO:0051402 IMP acts_upstream_of neuron apoptotic process 15380020 Process
20617 GO:0060079 IMP acts_upstream_of_or_within excitatory postsynaptic potential 17610578 Process
20617 GO:0060291 IMP acts_upstream_of_or_within long-term synaptic potentiation 17689254 Process
20617 GO:0061024 IMP acts_upstream_of_or_within membrane organization 14507911 Process
20617 GO:2000377 IMP involved_in regulation of reactive oxygen species metabolic process 25043722 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
20617 GO:0005515 IPI enables protein binding 17296554,22163275,24412932,24983211,27348587 Function
20617 GO:0042393 IDA enables histone binding 16959795 Function
20617 GO:0042802 IDA enables identical protein binding 10978144 Function
20617 GO:0050544 IDA enables arachidonic acid binding 16734431 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
20617 GO:0005634 IDA located_in nucleus 16959795 Component
20617 GO:0005737 IDA located_in cytoplasm 17475220,20457918 Component
20617 GO:0005829 IDA located_in cytosol 18980610 Component
20617 GO:0005856 IDA located_in cytoskeleton 17077307 Component
20617 GO:0005886 IDA located_in plasma membrane 17475220,25246573 Component
20617 GO:0016234 IDA located_in inclusion body 17222866,24076025 Component
20617 GO:0030672 IDA is_active_in synaptic vesicle membrane 28052246 Component
20617 GO:0030672 IEP is_active_in synaptic vesicle membrane 28052246 Component
20617 GO:0043025 IMP located_in neuronal cell body 26203154 Component
20617 GO:0043679 IDA located_in axon terminus 17296554 Component
20617 GO:0045202 IDA located_in synapse 10964942 Component
20617 GO:0045202 IMP located_in synapse 25009269 Component
20617 GO:0098793 IMP located_in presynapse 25009269 Component