Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 2065
  • Symbol: ERBB3
  • Description: erb-b2 receptor tyrosine kinase 3

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2065 GO:0004713 IDA NOT enables protein tyrosine kinase activity 7556068 Function
2065 GO:0005515 IPI enables protein binding 7592681,9516479,10572067,15282549,16273093,16832058,16843263,1..... Function
2065 GO:0019838 IPI enables growth factor binding 11389077 Function
2065 GO:0030296 IDA enables protein tyrosine kinase activator activity 7556068 Function
2065 GO:0031625 IPI enables ubiquitin protein ligase binding 27353365 Function
2065 GO:0038132 IDA enables neuregulin binding 20682778 Function
2065 GO:0042802 IPI enables identical protein binding 21575594,23436906 Function
2065 GO:0043125 IPI enables ErbB-3 class receptor binding 12000754 Function
2065 GO:0046982 IPI enables protein heterodimerization activity 7556068 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2065 GO:0005615 IDA located_in extracellular space 11389077 Component
2065 GO:0016323 IDA located_in basolateral plasma membrane 12646923 Component
2065 GO:0038143 IDA part_of ERBB3:ERBB2 complex 12000754 Component
2065 GO:0043235 IDA part_of receptor complex 23382219 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2065 GO:0007162 IDA involved_in negative regulation of cell adhesion 7556068 Process
2065 GO:0007165 IDA involved_in signal transduction 10572067 Process
2065 GO:0009968 IDA involved_in negative regulation of signal transduction 11389077 Process
2065 GO:0014065 IDA involved_in phosphatidylinositol 3-kinase signaling 7556068 Process
2065 GO:0042127 IDA involved_in regulation of cell population proliferation 11389077 Process
2065 GO:0051048 IDA involved_in negative regulation of secretion 10559227 Process
2065 GO:0051402 IMP involved_in neuron apoptotic process 17701904 Process
2065 GO:0061098 IMP involved_in positive regulation of protein tyrosine kinase activity 7556068 Process
2065 GO:0097192 IMP involved_in extrinsic apoptotic signaling pathway in absence of ligand 17701904 Process