Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 2068
  • Symbol: ERCC2
  • Description: ERCC excision repair 2, TFIIH core complex helicase subunit

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2068 GO:0000439 IDA part_of transcription factor TFIIH core complex 8692841,8692842 Component
2068 GO:0005634 IDA located_in nucleus 20797633,23585563 Component
2068 GO:0005654 IDA located_in nucleoplasm Component
2068 GO:0005669 IDA part_of transcription factor TFIID complex 27193682 Component
2068 GO:0005675 IDA part_of transcription factor TFIIH holo complex 9852112 Component
2068 GO:0005737 IDA located_in cytoplasm 20797633,23585563 Component
2068 GO:0005819 IDA located_in spindle 20797633 Component
2068 GO:0005829 IDA located_in cytosol Component
2068 GO:0070516 IDA part_of CAK-ERCC2 complex 8692841,8692842,11445587 Component
2068 GO:0071817 IDA part_of MMXD complex 20797633 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2068 GO:0005515 IPI enables protein binding 7663514,8652557,10801852,11445587,16669699,19934020,20797633,2..... Function
2068 GO:0030674 IPI enables protein-macromolecule adaptor activity 11445587 Function
2068 GO:0043139 IDA enables 5'-3' DNA helicase activity 8663148,11445587 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2068 GO:0006283 IDA involved_in transcription-coupled nucleotide-excision repair 8663148 Process
2068 GO:0006289 IMP involved_in nucleotide-excision repair 8692841 Process
2068 GO:0006366 IDA involved_in transcription by RNA polymerase II 8692841,8692842,9852112 Process
2068 GO:0006915 IMP involved_in apoptotic process 8675009 Process
2068 GO:0006979 IMP involved_in response to oxidative stress 17614221 Process
2068 GO:0007059 IMP involved_in chromosome segregation 20797633 Process
2068 GO:0035315 IMP involved_in hair cell differentiation 11335038 Process
2068 GO:1901990 IMP involved_in regulation of mitotic cell cycle phase transition 17088560 Process