Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 2071
  • Symbol: ERCC3
  • Description: ERCC excision repair 3, TFIIH core complex helicase subunit

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2071 GO:0000439 IDA part_of transcription factor TFIIH core complex 8692841,8692842 Component
2071 GO:0005654 IDA located_in nucleoplasm Component
2071 GO:0005669 IDA part_of transcription factor TFIID complex 27193682 Component
2071 GO:0005675 IDA part_of transcription factor TFIIH holo complex 9852112 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2071 GO:0000717 IMP involved_in nucleotide-excision repair, DNA duplex unwinding 17466626 Process
2071 GO:0006265 IMP involved_in DNA topological change 8663148 Process
2071 GO:0006281 IMP involved_in DNA repair 2167179 Process
2071 GO:0006283 IDA involved_in transcription-coupled nucleotide-excision repair 8663148 Process
2071 GO:0006289 IMP involved_in nucleotide-excision repair 8692841,17466626,17509950 Process
2071 GO:0006366 IDA involved_in transcription by RNA polymerase II 8692841,9852112 Process
2071 GO:0006366 IMP involved_in transcription by RNA polymerase II 8663148 Process
2071 GO:0006915 IMP involved_in apoptotic process 8675009 Process
2071 GO:0006979 IMP involved_in response to oxidative stress 17614221 Process
2071 GO:0008104 IMP involved_in protein localization 17509950 Process
2071 GO:0009411 IMP involved_in response to UV 17509950 Process
2071 GO:0035315 IMP involved_in hair cell differentiation 11335038 Process
2071 GO:0043065 IDA involved_in positive regulation of apoptotic process 16914395 Process
2071 GO:1901990 IMP involved_in regulation of mitotic cell cycle phase transition 17088560 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2071 GO:0005515 IPI enables protein binding 7663514,7926747,8652557,8692842,9173976,10734143,10801852,1666..... Function
2071 GO:0016887 IDA enables ATP hydrolysis activity 17466626 Function
2071 GO:0043138 IDA enables 3'-5' DNA helicase activity 17466626 Function
2071 GO:0043138 IMP enables 3'-5' DNA helicase activity 8663148 Function