Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 21413
  • Symbol: Tcf4
  • Description: transcription factor 4

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
21413 GO:0000122 IDA acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II Process
21413 GO:0006355 IDA acts_upstream_of_or_within regulation of DNA-templated transcription 15351717 Process
21413 GO:0010629 IDA acts_upstream_of_or_within negative regulation of gene expression 20231428 Process
21413 GO:0016525 IDA acts_upstream_of_or_within negative regulation of angiogenesis 20231428 Process
21413 GO:0042118 IDA acts_upstream_of_or_within endothelial cell activation 20231428 Process
21413 GO:0045666 IDA involved_in positive regulation of neuron differentiation 18214987 Process
21413 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 8978694 Process
21413 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 25620640 Process
21413 GO:0065004 IDA involved_in protein-DNA complex assembly 8978694 Process
21413 GO:1900746 IDA acts_upstream_of_or_within regulation of vascular endothelial growth factor signaling pathway 20231428 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
21413 GO:0000977 IMP enables RNA polymerase II transcription regulatory region sequence-specific DNA binding 25620640 Function
21413 GO:0000978 IDA enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 8978694,23740243 Function
21413 GO:0000981 IDA enables DNA-binding transcription factor activity, RNA polymerase II-specific 8978694 Function
21413 GO:0001093 IDA enables TFIIB-class transcription factor binding 8978694 Function
21413 GO:0001228 IDA enables DNA-binding transcription activator activity, RNA polymerase II-specific 8978694 Function
21413 GO:0001228 IMP enables DNA-binding transcription activator activity, RNA polymerase II-specific 25620640 Function
21413 GO:0003677 IDA enables DNA binding 14762206 Function
21413 GO:0003682 IDA enables chromatin binding 24192035 Function
21413 GO:0003714 IDA enables transcription corepressor activity 8999959 Function
21413 GO:0005515 IPI enables protein binding 8999959,11076679,11591653,15351717,16407974,17878293,18214987,..... Function
21413 GO:0043621 IMP enables protein self-association 20231428 Function
21413 GO:0046982 IDA enables protein heterodimerization activity 18214987 Function
21413 GO:0070888 IDA enables E-box binding 8978694,18214987 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
21413 GO:0005634 IDA located_in nucleus 19796622,20231428 Component
21413 GO:0005667 IDA part_of transcription regulator complex 8978694,15351717 Component