Gene Ontology

Gene Info

• Species: Mouse (Mus musculus)
• GeneID: 22346
• Symbol: Vhl
• Description: von Hippel-Lindau tumor suppressor

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
22346	GO:0001525	IMP	acts_upstream_of_or_within	angiogenesis	16537898	Process
22346	GO:0003309	IMP	acts_upstream_of_or_within	type B pancreatic cell differentiation	25186293	Process
22346	GO:0003310	IMP	acts_upstream_of_or_within	pancreatic A cell differentiation	25186293	Process
22346	GO:0006582	IMP	acts_upstream_of_or_within	melanin metabolic process	22627278	Process
22346	GO:0010468	IMP	acts_upstream_of_or_within	regulation of gene expression	22627278	Process
22346	GO:0010498	IMP	acts_upstream_of_or_within	proteasomal protein catabolic process	17981124	Process
22346	GO:0010629	IMP	acts_upstream_of_or_within	negative regulation of gene expression	22627278	Process
22346	GO:0015031	IDA	acts_upstream_of_or_within	protein transport	16129783	Process
22346	GO:0030163	IMP	acts_upstream_of_or_within	protein catabolic process	12832481	Process
22346	GO:0030198	IMP	acts_upstream_of_or_within	extracellular matrix organization	16537898	Process
22346	GO:0032880	IMP	acts_upstream_of_or_within	regulation of protein localization	22627278	Process
22346	GO:0043534	IMP	acts_upstream_of_or_within	blood vessel endothelial cell migration	16537898	Process
22346	GO:0045446	IMP	acts_upstream_of	endothelial cell differentiation	25186293	Process
22346	GO:0045602	IMP	acts_upstream_of_or_within	negative regulation of endothelial cell differentiation	25186293	Process
22346	GO:0048069	IMP	acts_upstream_of_or_within	eye pigmentation	22627278	Process
22346	GO:0048593	IGI	acts_upstream_of_or_within	camera-type eye morphogenesis	22627278	Process
22346	GO:0048593	IMP	acts_upstream_of_or_within	camera-type eye morphogenesis	22627278	Process
22346	GO:0048877	IMP	acts_upstream_of_or_within	homeostasis of number of retina cells	22627278	Process
22346	GO:0050679	IMP	acts_upstream_of_or_within	positive regulation of epithelial cell proliferation	22627278	Process
22346	GO:0061072	IGI	acts_upstream_of_or_within	iris morphogenesis	22627278	Process
22346	GO:0061072	IMP	acts_upstream_of_or_within	iris morphogenesis	22627278	Process
22346	GO:0061073	IMP	acts_upstream_of_or_within	ciliary body morphogenesis	22627278	Process
22346	GO:0070243	IGI	acts_upstream_of_or_within	regulation of thymocyte apoptotic process	15456877	Process
22346	GO:0070244	IMP	acts_upstream_of_or_within	negative regulation of thymocyte apoptotic process	15456877	Process
22346	GO:0097411	IMP	acts_upstream_of	hypoxia-inducible factor-1alpha signaling pathway	25186293	Process
22346	GO:0099175	IDA	involved_in	regulation of postsynapse organization	26972007	Process
22346	GO:0099175	IEP	involved_in	regulation of postsynapse organization	26972007	Process
22346	GO:0099175	IMP	involved_in	regulation of postsynapse organization	26972007	Process
22346	GO:0099175	IPI	involved_in	regulation of postsynapse organization	26972007	Process
22346	GO:0140252	IDA	involved_in	regulation protein catabolic process at postsynapse	26972007	Process
22346	GO:0140252	IEP	involved_in	regulation protein catabolic process at postsynapse	26972007	Process
22346	GO:0140252	IMP	involved_in	regulation protein catabolic process at postsynapse	26972007	Process
22346	GO:1902072	IMP	acts_upstream_of_or_within	negative regulation of hypoxia-inducible factor-1alpha signaling pathway	25186293	Process
22346	GO:2001233	IGI	acts_upstream_of_or_within	regulation of apoptotic signaling pathway	15456877	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
22346	GO:0005515	IPI	enables	protein binding	15601820	Function
22346	GO:0044877	IDA	enables	protein-containing complex binding	17825299	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
22346	GO:0005634	IDA	located_in	nucleus	16129783	Component
22346	GO:0005654	IDA	located_in	nucleoplasm	16129783	Component
22346	GO:0005730	IDA	located_in	nucleolus	16129783	Component
22346	GO:0005737	IDA	located_in	cytoplasm	16129783	Component
22346	GO:0005929	IDA	located_in	cilium	17825299	Component
22346	GO:0014069	IDA	is_active_in	postsynaptic density	26972007	Component
22346	GO:0014069	IEP	is_active_in	postsynaptic density	26972007	Component
22346	GO:0031462	IDA	part_of	Cul2-RING ubiquitin ligase complex	16129783	Component
22346	GO:0098978	IDA	is_active_in	glutamatergic synapse	26972007	Component
22346	GO:0098978	IEP	is_active_in	glutamatergic synapse	26972007	Component
22346	GO:0098978	IMP	is_active_in	glutamatergic synapse	26972007	Component
22346	GO:0098978	IPI	is_active_in	glutamatergic synapse	26972007	Component