Gene Ontology

Gene Info

• Species: Mouse (Mus musculus)
• GeneID: 22393
• Symbol: Wfs1
• Description: wolframin ER transmembrane glycoprotein

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
22393	GO:0005783	IDA	located_in	endoplasmic reticulum	16087305	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
22393	GO:0017148	IMP	involved_in	negative regulation of translation	19911006	Process
22393	GO:0030433	IMP	involved_in	ubiquitin-dependent ERAD pathway	20160352	Process
22393	GO:0030968	IMP	involved_in	endoplasmic reticulum unfolded protein response	16571599,19911006	Process
22393	GO:0031398	IMP	involved_in	positive regulation of protein ubiquitination	20160352	Process
22393	GO:0034976	IDA	involved_in	response to endoplasmic reticulum stress	15994758	Process
22393	GO:0045927	IMP	involved_in	positive regulation of growth	19293327	Process
22393	GO:0050821	IMP	involved_in	protein stabilization	20160352	Process
22393	GO:1902236	IMP	involved_in	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	16571599	Process
22393	GO:1904294	IMP	involved_in	positive regulation of ERAD pathway	19911006	Process
22393	GO:2000675	IMP	involved_in	negative regulation of type B pancreatic cell apoptotic process	16087305,16571599	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
22393	GO:0051117	IDA	enables	ATPase binding	17947299	Function