Gene Ontology

Gene Info

• Species: Mouse (Mus musculus)
• GeneID: 22427
• Symbol: Wrn
• Description: Werner syndrome RecQ like helicase

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
22427	GO:0000723	IGI	acts_upstream_of_or_within	telomere maintenance	15235603,15367665	Process
22427	GO:0000723	IMP	acts_upstream_of_or_within	telomere maintenance	12707040	Process
22427	GO:0006259	IMP	acts_upstream_of_or_within	DNA metabolic process	11756244,12707040	Process
22427	GO:0006260	IGI	involved_in	DNA replication	26195664	Process
22427	GO:0006260	IMP	acts_upstream_of_or_within	DNA replication	9789047	Process
22427	GO:0006260	IMP	involved_in	DNA replication	26195664	Process
22427	GO:0008340	IGI	acts_upstream_of_or_within	determination of adult lifespan	15235603	Process
22427	GO:0040009	IMP	acts_upstream_of_or_within	regulation of growth rate	12707040	Process
22427	GO:0044806	IGI	involved_in	G-quadruplex DNA unwinding	26195664	Process
22427	GO:0044806	IMP	involved_in	G-quadruplex DNA unwinding	26195664	Process
22427	GO:0090399	IMP	acts_upstream_of_or_within	replicative senescence	10757812	Process

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
22427	GO:0000781	IMP	located_in	chromosome, telomeric region	26195664	Component
22427	GO:0005634	IDA	located_in	nucleus	9789047	Component
22427	GO:0005654	IDA	located_in	nucleoplasm	11420665	Component
22427	GO:0005657	IMP	located_in	replication fork	26195664	Component
22427	GO:0005730	IDA	NOT located_in	nucleolus	11420665	Component

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
22427	GO:0005515	IPI	enables	protein binding	11301316	Function
22427	GO:0008408	IDA	enables	3'-5' exonuclease activity	10871373	Function