Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 22894
• Symbol: DIS3
• Description: DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
22894	GO:0000175	IMP	enables	3'-5'-RNA exonuclease activity	20531386	Function
22894	GO:0004519	IMP	enables	endonuclease activity	20531386	Function
22894	GO:0005085	IDA	enables	guanyl-nucleotide exchange factor activity	9562621	Function
22894	GO:0005515	IPI	enables	protein binding	15231747,20531386,20531389,21255825,23756462,25220460.....	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
22894	GO:0000176	IDA	part_of	nuclear exosome (RNase complex)	20531386	Component
22894	GO:0005634	IDA	located_in	nucleus	20531386	Component
22894	GO:0005654	IDA	located_in	nucleoplasm	20531389	Component
22894	GO:0005730	IDA	NOT located_in	nucleolus	20531386	Component
22894	GO:0005829	IDA	located_in	cytosol	20531386	Component
22894	GO:0016020	HDA	located_in	membrane	19946888	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
22894	GO:0006396	IDA	involved_in	RNA processing	17174896	Process
22894	GO:0006401	IDA	involved_in	RNA catabolic process	17174896	Process
22894	GO:0016075	IMP	involved_in	rRNA catabolic process	20368444	Process
22894	GO:0071034	IMP	involved_in	CUT catabolic process	19056938	Process