Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 23013
• Symbol: SPEN
• Description: spen family transcriptional repressor

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
23013	GO:0000122	IDA	involved_in	negative regulation of transcription by RNA polymerase II	16287852	Process
23013	GO:0045892	IDA	involved_in	negative regulation of DNA-templated transcription	16129689	Process
23013	GO:0050769	IMP	involved_in	positive regulation of neurogenesis	16287852	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
23013	GO:0003714	IDA	enables	transcription corepressor activity	16287852	Function
23013	GO:0003723	HDA	enables	RNA binding	22658674,22681889	Function
23013	GO:0005515	IPI	enables	protein binding	16129689,16287852,17474147,21102556,24268649,25609649,35044719.....	Function
23013	GO:0061629	IPI	enables	RNA polymerase II-specific DNA-binding transcription factor binding	16287852	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
23013	GO:0005654	IDA	located_in	nucleoplasm		Component
23013	GO:0017053	IDA	part_of	transcription repressor complex	16287852	Component
23013	GO:0070062	HDA	located_in	extracellular exosome	19056867	Component