Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 23019
  • Symbol: CNOT1
  • Description: CCR4-NOT transcription complex subunit 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
23019 GO:0000122 IDA involved_in negative regulation of transcription by RNA polymerase II 16778766 Process
23019 GO:0010606 IDA involved_in positive regulation of cytoplasmic mRNA processing body assembly 21976065 Process
23019 GO:0017148 IDA involved_in negative regulation of translation 24736845 Process
23019 GO:0033147 IDA involved_in negative regulation of intracellular estrogen receptor signaling pathway 16778766 Process
23019 GO:0035195 IDA involved_in miRNA-mediated gene silencing 23172285,24768540 Process
23019 GO:0048387 IDA involved_in negative regulation of retinoic acid receptor signaling pathway 16778766 Process
23019 GO:0060213 IDA involved_in positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 23644599 Process
23019 GO:0060213 IMP involved_in positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 21278420 Process
23019 GO:0061014 IMP involved_in positive regulation of mRNA catabolic process 22977175 Process
23019 GO:1900153 IMP involved_in positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 21278420 Process
23019 GO:2000036 IMP involved_in regulation of stem cell population maintenance 22367759 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
23019 GO:0000932 IDA located_in P-body 21976065 Component
23019 GO:0005615 HDA located_in extracellular space 22664934 Component
23019 GO:0005829 IDA located_in cytosol Component
23019 GO:0016020 HDA located_in membrane 19946888 Component
23019 GO:0030014 IDA part_of CCR4-NOT complex 19558367 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
23019 GO:0003723 HDA enables RNA binding 22658674,22681889 Function
23019 GO:0004535 IDA contributes_to poly(A)-specific ribonuclease activity 21976065 Function
23019 GO:0005515 IPI enables protein binding 10637334,16778766,17452450,18377426,20584987,21278420,21981923..... Function
23019 GO:0019904 IPI enables protein domain specific binding 24768540 Function
23019 GO:0030331 IDA enables nuclear estrogen receptor binding 16778766 Function
23019 GO:0042974 IDA enables nuclear retinoic acid receptor binding 16778766 Function
23019 GO:0060090 IDA enables molecular adaptor activity 22977175 Function
23019 GO:0070016 IPI enables armadillo repeat domain binding 24768540 Function