Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 2308
  • Symbol: FOXO1
  • Description: forkhead box O1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2308 GO:0001228 IDA enables DNA-binding transcription activator activity, RNA polymerase II-specific 17024043 Function
2308 GO:0003676 EXP enables nucleic acid binding 18786403 Function
2308 GO:0003700 IDA enables DNA-binding transcription factor activity 17024043 Function
2308 GO:0003700 IMP enables DNA-binding transcription factor activity 31063815 Function
2308 GO:0005515 IPI enables protein binding 11237865,11353774,15220471,15692560,15890677,17030088,18235501..... Function
2308 GO:0008013 IDA enables beta-catenin binding 15905404 Function
2308 GO:0031625 IPI enables ubiquitin protein ligase binding 20543840 Function
2308 GO:0043565 IDA enables sequence-specific DNA binding 12228231 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2308 GO:0005634 IDA is_active_in nucleus 25009184 Component
2308 GO:0005634 IDA located_in nucleus 11311120,12228231,18680538,20543840,31063815 Component
2308 GO:0005737 IDA located_in cytoplasm 11237865,11311120,12228231,20543840,25009184,31063815..... Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2308 GO:0006915 IMP involved_in apoptotic process 31063815 Process
2308 GO:0009267 IDA involved_in cellular response to starvation 20543840 Process
2308 GO:0010508 IMP involved_in positive regulation of autophagy 20543840 Process
2308 GO:0032873 IDA involved_in negative regulation of stress-activated MAPK cascade 19696738 Process
2308 GO:0043065 IMP involved_in positive regulation of apoptotic process 20543840 Process
2308 GO:0043066 IDA involved_in negative regulation of apoptotic process 10871843 Process
2308 GO:0045722 IDA involved_in positive regulation of gluconeogenesis 17024043,25009184 Process
2308 GO:0045732 IMP involved_in positive regulation of protein catabolic process 20543840 Process
2308 GO:0045893 IDA involved_in positive regulation of DNA-templated transcription 7862145,10871843,12228231 Process
2308 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 10871843,12228231 Process
2308 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 27577745 Process
2308 GO:0071455 IDA involved_in cellular response to hyperoxia 20543840 Process