Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 2309
  • Symbol: FOXO3
  • Description: forkhead box O3

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2309 GO:0000122 IDA involved_in negative regulation of transcription by RNA polymerase II 18393360,20371612,21621563 Process
2309 GO:0000122 IMP involved_in negative regulation of transcription by RNA polymerase II 18787191 Process
2309 GO:0006390 IMP involved_in mitochondrial transcription 29445193 Process
2309 GO:0006417 IDA involved_in regulation of translation 21329882 Process
2309 GO:0030336 IMP involved_in negative regulation of cell migration 19188590 Process
2309 GO:0033209 IMP involved_in tumor necrosis factor-mediated signaling pathway 15084260 Process
2309 GO:0042149 IDA involved_in cellular response to glucose starvation 29445193 Process
2309 GO:0043065 IDA involved_in positive regulation of apoptotic process 20371612 Process
2309 GO:0043525 IMP involved_in positive regulation of neuron apoptotic process 10102273 Process
2309 GO:0045591 IDA involved_in positive regulation of regulatory T cell differentiation 30513302 Process
2309 GO:0045648 IDA acts_upstream_of_or_within positive regulation of erythrocyte differentiation 14734530 Process
2309 GO:0045893 IDA involved_in positive regulation of DNA-templated transcription 10102273,15084260 Process
2309 GO:0045944 IDA acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 14734530 Process
2309 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 10102273 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2309 GO:0001227 IDA enables DNA-binding transcription repressor activity, RNA polymerase II-specific 20371612 Function
2309 GO:0003677 IDA enables DNA binding 21329882 Function
2309 GO:0003700 IDA enables DNA-binding transcription factor activity 14734530,30513302 Function
2309 GO:0005515 IPI enables protein binding 10102273,11864996,14976264,15084259,15084260,15126506,16809346..... Function
2309 GO:0008013 IPI enables beta-catenin binding 15905404 Function
2309 GO:0019901 IPI enables protein kinase binding 16751106,18593906,21329882 Function
2309 GO:0034246 IMP enables mitochondrial transcription factor activity 29445193 Function
2309 GO:0043565 IDA enables sequence-specific DNA binding 10102273 Function
2309 GO:1990837 IDA enables sequence-specific double-stranded DNA binding 28473536 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2309 GO:0005634 IDA located_in nucleus 10102273,15084260,16751106,18393360,21329882,22761832,23283301..... Component
2309 GO:0005634 IMP located_in nucleus 29445193 Component
2309 GO:0005654 IDA located_in nucleoplasm Component
2309 GO:0005737 IDA located_in cytoplasm 10102273,15084260,16751106,20371612,21329882,23283301..... Component
2309 GO:0005739 IDA colocalizes_with mitochondrion 23283301 Component
2309 GO:0005741 IDA located_in mitochondrial outer membrane 29445193 Component
2309 GO:0005759 IDA colocalizes_with mitochondrial matrix 29445193 Component
2309 GO:0005829 IDA located_in cytosol 23640897 Component
2309 GO:0032991 IDA part_of protein-containing complex 23283301,29445193 Component
2309 GO:0090571 IPI part_of RNA polymerase II transcription repressor complex 18393360 Component