Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 23189
  • Symbol: KANK1
  • Description: KN motif and ankyrin repeat domains 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
23189 GO:0005515 IPI enables protein binding 16968744,18458160,19171758,19559006,22084092,26496610,29183992..... Function
23189 GO:0008013 IDA enables beta-catenin binding 16968744 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
23189 GO:0005737 IDA located_in cytoplasm 12133830 Component
23189 GO:0005886 IDA located_in plasma membrane Component
23189 GO:0032587 IDA located_in ruffle membrane 19559006 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
23189 GO:0008283 IMP involved_in cell population proliferation 12133830 Process
23189 GO:0010977 IDA involved_in negative regulation of neuron projection development 19171758 Process
23189 GO:0030036 IMP involved_in actin cytoskeleton organization 12133830 Process
23189 GO:0030177 IDA involved_in positive regulation of Wnt signaling pathway 16968744 Process
23189 GO:0030336 IMP involved_in negative regulation of cell migration 18458160 Process
23189 GO:0030837 IDA acts_upstream_of_or_within negative regulation of actin filament polymerization 17996375 Process
23189 GO:0030837 IDA involved_in negative regulation of actin filament polymerization 18458160 Process
23189 GO:0035023 IMP involved_in regulation of Rho protein signal transduction 25961457 Process
23189 GO:0035024 IMP involved_in negative regulation of Rho protein signal transduction 18458160 Process
23189 GO:0046627 IMP involved_in negative regulation of insulin receptor signaling pathway 18458160 Process
23189 GO:0090263 IMP involved_in positive regulation of canonical Wnt signaling pathway 16968744 Process
23189 GO:0090303 IMP involved_in positive regulation of wound healing 22084092 Process
23189 GO:0090521 IMP involved_in podocyte cell migration 25961457 Process
23189 GO:1900025 IDA involved_in negative regulation of substrate adhesion-dependent cell spreading 19171758 Process
23189 GO:1900028 IDA involved_in negative regulation of ruffle assembly 19171758 Process
23189 GO:2000114 IMP involved_in regulation of establishment of cell polarity 22084092 Process
23189 GO:2000393 IDA involved_in negative regulation of lamellipodium morphogenesis 19171758 Process