Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 23400
• Symbol: ATP13A2
• Description: ATPase cation transporting 13A2

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
23400	GO:0005515	IPI	enables	protein binding	22645275,27278822	Function
23400	GO:0015203	IDA	enables	polyamine transmembrane transporter activity	31996848	Function
23400	GO:0070300	IDA	enables	phosphatidic acid binding	26134396	Function
23400	GO:0080025	IDA	enables	phosphatidylinositol-3,5-bisphosphate binding	26134396	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
23400	GO:0005764	IDA	located_in	lysosome	16964263,21542062,24603074,25392495	Component
23400	GO:0005765	HDA	located_in	lysosomal membrane	17897319	Component
23400	GO:0005765	IDA	located_in	lysosomal membrane	23499937,26134396,29505581	Component
23400	GO:0005770	IDA	located_in	late endosome	25392495	Component
23400	GO:0005771	IDA	located_in	multivesicular body	24603074,25392495	Component
23400	GO:0005776	IDA	located_in	autophagosome	24603074	Component
23400	GO:0030133	IDA	located_in	transport vesicle	22186024	Component
23400	GO:0031902	IDA	located_in	late endosome membrane	29505581	Component
23400	GO:0031982	IDA	located_in	vesicle	24603074	Component
23400	GO:0043005	IDA	located_in	neuron projection	22186024	Component
23400	GO:0043025	IDA	located_in	neuronal cell body	22186024	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
23400	GO:0006874	IDA	involved_in	intracellular calcium ion homeostasis	22186024	Process
23400	GO:0006879	IMP	involved_in	intracellular iron ion homeostasis	26818499	Process
23400	GO:0006882	IMP	involved_in	intracellular zinc ion homeostasis	24334770,24603074	Process
23400	GO:0006914	IMP	involved_in	autophagy	27278822	Process
23400	GO:0007041	IMP	involved_in	lysosomal transport	31996848	Process
23400	GO:0010628	IMP	involved_in	positive regulation of gene expression	27278822	Process
23400	GO:0010821	IDA	involved_in	regulation of mitochondrion organization	22186024	Process
23400	GO:0010821	IMP	involved_in	regulation of mitochondrion organization	22198378	Process
23400	GO:0016241	IMP	involved_in	regulation of macroautophagy	22198378	Process
23400	GO:0016243	IDA	involved_in	regulation of autophagosome size	22186024	Process
23400	GO:0034599	IMP	involved_in	cellular response to oxidative stress	26134396	Process
23400	GO:0050714	IMP	involved_in	positive regulation of protein secretion	25392495	Process
23400	GO:0052548	IMP	involved_in	regulation of endopeptidase activity	23499937	Process
23400	GO:0055088	IMP	involved_in	lipid homeostasis	31132336	Process
23400	GO:0061462	IMP	involved_in	protein localization to lysosome	30538141	Process
23400	GO:0061909	IMP	involved_in	autophagosome-lysosome fusion	30538141	Process
23400	GO:0071287	IMP	involved_in	cellular response to manganese ion	22285144	Process
23400	GO:0097734	IMP	involved_in	extracellular exosome biogenesis	25392495	Process
23400	GO:1900180	IMP	involved_in	regulation of protein localization to nucleus	27278822	Process
23400	GO:1902047	IDA	involved_in	polyamine transmembrane transport	23205587	Process
23400	GO:1903543	IDA	involved_in	positive regulation of exosomal secretion	24603074	Process
23400	GO:1903543	IMP	involved_in	positive regulation of exosomal secretion	25392495	Process
23400	GO:1903710	IMP	involved_in	spermine transmembrane transport	31996848	Process
23400	GO:1905037	IDA	involved_in	autophagosome organization	22186024	Process
23400	GO:1905165	IGI	involved_in	regulation of lysosomal protein catabolic process	24334770	Process
23400	GO:1905165	IMP	involved_in	regulation of lysosomal protein catabolic process	23499937	Process
23400	GO:1990938	IMP	involved_in	peptidyl-aspartic acid autophosphorylation	26134396	Process
23400	GO:2000152	IMP	involved_in	regulation of ubiquitin-specific protease activity	27278822	Process