Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 23513
  • Symbol: SCRIB
  • Description: scribble planar cell polarity protein

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
23513 GO:0001843 IMP involved_in neural tube closure 22095531 Process
23513 GO:0001921 IMP involved_in positive regulation of receptor recycling 15775968 Process
23513 GO:0008283 IDA involved_in cell population proliferation 16965391 Process
23513 GO:0016477 IMP involved_in cell migration 18716323 Process
23513 GO:0030859 IMP involved_in polarized epithelial cell differentiation 27380321 Process
23513 GO:0035089 IMP involved_in establishment of apical/basal cell polarity 19041750 Process
23513 GO:0043065 IMP involved_in positive regulation of apoptotic process 19041750 Process
23513 GO:0045930 IDA involved_in negative regulation of mitotic cell cycle 16965391 Process
23513 GO:0050918 IMP involved_in positive chemotaxis 18716323 Process
23513 GO:0060561 IMP involved_in apoptotic process involved in morphogenesis 19041750 Process
23513 GO:0071896 IMP involved_in protein localization to adherens junction 16611247 Process
23513 GO:0090630 IMP involved_in activation of GTPase activity 19041750 Process
23513 GO:0098609 IGI involved_in cell-cell adhesion 16344308 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
23513 GO:0005515 IPI enables protein binding 15182672,15649318,15775968,15975580,16103886,16137684,16611247..... Function
23513 GO:0035591 IDA enables signaling adaptor activity 27380321 Function
23513 GO:0045296 HDA enables cadherin binding 25468996 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
23513 GO:0005654 IDA located_in nucleoplasm Component
23513 GO:0005886 IDA colocalizes_with plasma membrane 16611247 Component
23513 GO:0005886 IDA located_in plasma membrane 15182672,28169360 Component
23513 GO:0005911 IDA located_in cell-cell junction 15649318,27380321 Component
23513 GO:0005912 IDA located_in adherens junction 16965391 Component
23513 GO:0030054 IDA located_in cell junction Component
23513 GO:0031252 IDA colocalizes_with cell leading edge 18716323 Component
23513 GO:0034750 IDA part_of Scrib-APC-beta-catenin complex 16611247 Component
23513 GO:0042734 IDA colocalizes_with presynaptic membrane 15182672 Component
23513 GO:0045211 IDA colocalizes_with postsynaptic membrane 15182672 Component
23513 GO:0070062 HDA located_in extracellular exosome 20458337 Component