Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 238
• Symbol: ALK
• Description: ALK receptor tyrosine kinase

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
238	GO:0004713	IDA	enables	protein tyrosine kinase activity	9174053	Function
238	GO:0004714	IDA	enables	transmembrane receptor protein tyrosine kinase activity	9174053,30061385,34646012	Function
238	GO:0005515	IPI	enables	protein binding	17681947,22939624,26418745,35384245	Function
238	GO:0008201	IDA	enables	heparin binding	25605972,34646012	Function
238	GO:0030298	IDA	enables	receptor signaling protein tyrosine kinase activator activity	30061385,34646012	Function
238	GO:0042802	IPI	enables	identical protein binding	25517749	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
238	GO:0005886	IDA	is_active_in	plasma membrane	34646012,34819673	Component
238	GO:0005886	IDA	located_in	plasma membrane	9174053	Component
238	GO:0032991	IDA	part_of	protein-containing complex	23382219	Component
238	GO:0070062	HDA	located_in	extracellular exosome	19056867	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
238	GO:0007169	IDA	involved_in	transmembrane receptor protein tyrosine kinase signaling pathway	25605972,30061385,34646012	Process
238	GO:0016310	IDA	involved_in	phosphorylation	9174053	Process
238	GO:0038083	IDA	involved_in	peptidyl-tyrosine autophosphorylation	30061385,34646012	Process
238	GO:0046777	IDA	acts_upstream_of_or_within	protein autophosphorylation	9174053	Process
238	GO:0046777	IDA	involved_in	protein autophosphorylation	9174053	Process