Gene Ontology

Gene Info

  • Species: Rat (Rattus norvegicus)
  • GeneID: 24385
  • Symbol: Gck
  • Description: glucokinase

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
24385 GO:0000287 IDA enables magnesium ion binding 12513690 Function
24385 GO:0004340 IDA enables glucokinase activity 4273555,4353083,6477520,7742312,11250924,12513690,15138155..... Function
24385 GO:0005515 IPI enables protein binding 10601273,16186382,19807849 Function
24385 GO:0005524 IDA enables ATP binding 12513690 Function
24385 GO:0005536 IDA enables glucose binding 4273555,15138155 Function
24385 GO:0005536 IPI enables glucose binding 12513690 Function
24385 GO:0008865 IDA enables fructokinase activity 6477520,7742312 Function
24385 GO:0019158 IDA enables mannokinase activity 7742312 Function
24385 GO:0019903 IPI enables protein phosphatase binding 10913113 Function
24385 GO:0043531 IDA enables ADP binding 12513690 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
24385 GO:0001678 IMP involved_in intracellular glucose homeostasis 16443775 Process
24385 GO:0005978 IDA involved_in glycogen biosynthetic process 17028192 Process
24385 GO:0006002 IDA involved_in fructose 6-phosphate metabolic process 6477520,7742312 Process
24385 GO:0006003 IDA involved_in fructose 2,6-bisphosphate metabolic process 17553851 Process
24385 GO:0006006 IDA involved_in glucose metabolic process 17553851 Process
24385 GO:0006013 IDA involved_in mannose metabolic process 7742312 Process
24385 GO:0006096 IDA involved_in glycolytic process 4273555,4353083 Process
24385 GO:0007204 IDA involved_in positive regulation of cytosolic calcium ion concentration 17360975 Process
24385 GO:0009749 IEP involved_in response to glucose 12086933 Process
24385 GO:0019932 IDA involved_in second-messenger-mediated signaling 11250924 Process
24385 GO:0032024 IDA involved_in positive regulation of insulin secretion 17028192,17360975 Process
24385 GO:0032811 IMP involved_in negative regulation of epinephrine secretion 18292346 Process
24385 GO:0032869 IDA involved_in cellular response to insulin stimulus 17470517 Process
24385 GO:0042149 IMP involved_in cellular response to glucose starvation 18292346 Process
24385 GO:0042327 IDA involved_in positive regulation of phosphorylation 17553851 Process
24385 GO:0044320 IDA involved_in cellular response to leptin stimulus 17470517 Process
24385 GO:0045821 IDA involved_in positive regulation of glycolytic process 17553851 Process
24385 GO:0046835 IDA involved_in carbohydrate phosphorylation 9109397,15138155 Process
24385 GO:0051156 IDA involved_in glucose 6-phosphate metabolic process 4273555,6477520,7742312,15138155 Process
24385 GO:0051594 IDA involved_in detection of glucose 17470517 Process
24385 GO:0055088 IDA involved_in lipid homeostasis 22925001 Process
24385 GO:1902659 IMP involved_in regulation of glucose mediated signaling pathway 16443775 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
24385 GO:0005634 IDA located_in nucleus 10601273 Component
24385 GO:0005654 IDA located_in nucleoplasm 12369705 Component
24385 GO:0005737 IDA located_in cytoplasm 10601273 Component
24385 GO:0005884 IDA colocalizes_with actin filament 9109397 Component
24385 GO:0005938 IDA located_in cell cortex 12369705 Component
24385 GO:0030141 IDA located_in secretory granule 9357983,10461810 Component
24385 GO:0045180 IDA located_in basal cortex 10071239 Component