Gene Ontology

Gene Info

  • Species: Rat (Rattus norvegicus)
  • GeneID: 24408
  • Symbol: Grin1
  • Description: glutamate ionotropic receptor NMDA type subunit 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
24408 GO:0001540 IDA enables amyloid-beta binding 17308309 Function
24408 GO:0004970 IDA enables ionotropic glutamate receptor activity 16477151 Function
24408 GO:0004972 IDA enables NMDA glutamate receptor activity 16477151,18177891,22098737,24876489,28384476 Function
24408 GO:0004972 IGI enables NMDA glutamate receptor activity 7929101 Function
24408 GO:0004972 IMP enables NMDA glutamate receptor activity 17050728 Function
24408 GO:0005102 IPI enables signaling receptor binding 12408866 Function
24408 GO:0005515 IPI enables protein binding 8780649,10618500,16054660,16495444,17658481,19103256,19243221,..... Function
24408 GO:0016594 IDA enables glycine binding 8011339,22098737,24876489 Function
24408 GO:0016595 IDA enables glutamate binding 8011339 Function
24408 GO:0019899 IPI enables enzyme binding 15069201 Function
24408 GO:0019902 IDA enables phosphatase binding 15102920 Function
24408 GO:0022843 IMP enables voltage-gated monoatomic cation channel activity 17050728 Function
24408 GO:0035254 IPI enables glutamate receptor binding 19298817 Function
24408 GO:0035255 IPI enables ionotropic glutamate receptor binding 10414981 Function
24408 GO:0042165 IDA enables neurotransmitter binding 16477151 Function
24408 GO:0044877 IDA enables protein-containing complex binding 21544205,22493736 Function
24408 GO:0044877 IPI enables protein-containing complex binding 17308309 Function
24408 GO:0099507 EXP enables ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 19666514 Function
24408 GO:0099507 IDA enables ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 19666514 Function
24408 GO:0099507 IMP enables ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 19666514 Function
24408 GO:1904315 IDA enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 12160751 Function
24408 GO:1904315 IMP enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 12160751 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
24408 GO:0005737 IDA located_in cytoplasm 17526495 Component
24408 GO:0005886 IDA located_in plasma membrane 18177891,24876489,28384476 Component
24408 GO:0009986 IDA located_in cell surface 17526495 Component
24408 GO:0017146 IDA part_of NMDA selective glutamate receptor complex 16477151,17050728,18177891,22493736,24876489,28384476..... Component
24408 GO:0032590 IDA located_in dendrite membrane 15620359 Component
24408 GO:0042734 IDA is_active_in presynaptic membrane 19666514 Component
24408 GO:0043025 IDA located_in neuronal cell body 10618500 Component
24408 GO:0043083 IDA located_in synaptic cleft 17207780 Component
24408 GO:0043195 IDA located_in terminal bouton 19666514 Component
24408 GO:0043197 IDA located_in dendritic spine 17207780 Component
24408 GO:0044307 IDA located_in dendritic branch 10618500 Component
24408 GO:0045202 IDA located_in synapse 15681343,15978582,17003121 Component
24408 GO:0048787 IDA is_active_in presynaptic active zone membrane 23159309 Component
24408 GO:0060076 IDA located_in excitatory synapse 19730411 Component
24408 GO:0097060 IDA located_in synaptic membrane 10414981 Component
24408 GO:0097060 IPI located_in synaptic membrane 17308309 Component
24408 GO:0098686 IDA is_active_in hippocampal mossy fiber to CA3 synapse 23159309 Component
24408 GO:0098688 IDA is_active_in parallel fiber to Purkinje cell synapse 19666514 Component
24408 GO:0098839 IDA is_active_in postsynaptic density membrane 23159309 Component
24408 GO:0098978 IDA is_active_in glutamatergic synapse 12160751 Component
24408 GO:0098978 IMP is_active_in glutamatergic synapse 12160751 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
24408 GO:0010524 IGI involved_in positive regulation of calcium ion transport into cytosol 17308309 Process
24408 GO:0014070 IEP involved_in response to organic cyclic compound 19322657 Process
24408 GO:0014075 IEP involved_in response to amine 19918184 Process
24408 GO:0035235 IDA involved_in ionotropic glutamate receptor signaling pathway 16477151,19793963 Process
24408 GO:0048511 IDA involved_in rhythmic process 16477151 Process
24408 GO:0051290 IDA involved_in protein heterotetramerization 24876489 Process
24408 GO:0051592 IEP involved_in response to calcium ion 19761817 Process
24408 GO:0051968 IDA involved_in positive regulation of synaptic transmission, glutamatergic 19793963 Process
24408 GO:0060992 IEP involved_in response to fungicide 19591855 Process
24408 GO:0065003 IDA involved_in protein-containing complex assembly 22493736 Process
24408 GO:0071287 IEP involved_in cellular response to manganese ion 19643132 Process
24408 GO:0098655 IDA involved_in monoatomic cation transmembrane transport 22246434 Process
24408 GO:1900149 IMP involved_in positive regulation of Schwann cell migration 26656067 Process
24408 GO:1902952 IGI involved_in positive regulation of dendritic spine maintenance 17360908 Process
24408 GO:1903428 IGI involved_in positive regulation of reactive oxygen species biosynthetic process 17308309 Process
24408 GO:1904062 IDA involved_in regulation of monoatomic cation transmembrane transport 19793963,22246434 Process
24408 GO:2000463 IDA involved_in positive regulation of excitatory postsynaptic potential 12930820,19793963,22246434 Process
24408 GO:2001056 IGI involved_in positive regulation of cysteine-type endopeptidase activity 17526495 Process