Gene Ontology

Gene Info

• Species: Mouse (Mus musculus)
• GeneID: 244667
• Symbol: Disc1
• Description: disrupted in schizophrenia 1

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
244667	GO:0001764	IGI	acts_upstream_of_or_within	neuron migration	18762586	Process
244667	GO:0001764	IMP	acts_upstream_of_or_within	neuron migration	18762586,21471969	Process
244667	GO:0001764	IMP	involved_in	neuron migration	19502360	Process
244667	GO:0002052	IMP	involved_in	positive regulation of neuroblast proliferation	19303846	Process
244667	GO:0006511	IMP	acts_upstream_of	ubiquitin-dependent protein catabolic process	20880836	Process
244667	GO:0008104	IDA	acts_upstream_of_or_within	protein localization	20956536	Process
244667	GO:0010975	IMP	involved_in	regulation of neuron projection development	17825401,19778506	Process
244667	GO:0021799	IMP	involved_in	cerebral cortex radially oriented cell migration	20624590	Process
244667	GO:0021846	IMP	involved_in	cell proliferation in forebrain	20624590	Process
244667	GO:0030177	IMP	involved_in	positive regulation of Wnt signaling pathway	19303846,20624590	Process
244667	GO:0031929	IMP	involved_in	TOR signaling	19778506	Process
244667	GO:0032091	IDA	involved_in	negative regulation of protein binding	26078884	Process
244667	GO:0051560	IMP	acts_upstream_of_or_within	mitochondrial calcium ion homeostasis	20880836	Process
244667	GO:0060070	IMP	involved_in	canonical Wnt signaling pathway	20624590	Process
244667	GO:0070050	IMP	acts_upstream_of_or_within	neuron cellular homeostasis	20880836	Process
244667	GO:0090128	IMP	involved_in	regulation of synapse maturation	17825401	Process
244667	GO:0099175	IDA	involved_in	regulation of postsynapse organization	23826333	Process
244667	GO:0099175	IMP	involved_in	regulation of postsynapse organization	23826333	Process
244667	GO:1905515	IMP	acts_upstream_of_or_within	non-motile cilium assembly	20531939	Process
244667	GO:2000060	IMP	acts_upstream_of_or_within	positive regulation of ubiquitin-dependent protein catabolic process	20880836	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
244667	GO:0005515	IPI	enables	protein binding	18983980,19303846,19778506,20624590,20956536,21422296,30488644.....	Function
244667	GO:0042802	IPI	enables	identical protein binding	30561706	Function
244667	GO:0060090	IDA	enables	molecular adaptor activity	18983980	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
244667	GO:0005813	IDA	located_in	centrosome	18983980	Component
244667	GO:0005813	IMP	located_in	centrosome	20956536	Component
244667	GO:0008021	IDA	located_in	synaptic vesicle	18983980	Component
244667	GO:0014069	IDA	located_in	postsynaptic density	18983980	Component
244667	GO:0036064	IDA	located_in	ciliary basal body	22031837	Component
244667	GO:0098978	IDA	is_active_in	glutamatergic synapse	23826333	Component
244667	GO:0098978	IMP	is_active_in	glutamatergic synapse	23826333	Component