Gene Ontology

Gene Info

  • Species: Rat (Rattus norvegicus)
  • GeneID: 24514
  • Symbol: Jak2
  • Description: Janus kinase 2

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
24514 GO:0000791 IDA part_of euchromatin 8756581 Component
24514 GO:0098794 IDA is_active_in postsynapse 22284190 Component
24514 GO:0098978 EXP is_active_in glutamatergic synapse 22284190 Component
24514 GO:0098978 IDA is_active_in glutamatergic synapse 22284190 Component
24514 GO:0098978 IMP is_active_in glutamatergic synapse 22284190 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
24514 GO:0004713 IMP enables protein tyrosine kinase activity 15659221 Function
24514 GO:0005131 IPI enables growth hormone receptor binding 10502458,11244571 Function
24514 GO:0005515 IPI enables protein binding 8912646,16055727 Function
24514 GO:0031702 IPI enables type 1 angiotensin receptor binding 9287353,9314843 Function
24514 GO:0033130 IPI enables acetylcholine receptor binding 12244045 Function
24514 GO:0043548 IPI enables phosphatidylinositol 3-kinase binding 15530849 Function
24514 GO:0043560 IPI enables insulin receptor substrate binding 15701573 Function
24514 GO:0051428 IPI enables peptide hormone receptor binding 11244571 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
24514 GO:0006979 IMP involved_in response to oxidative stress 16269269 Process
24514 GO:0007186 IMP involved_in G protein-coupled receptor signaling pathway 17021051 Process
24514 GO:0007204 IMP involved_in positive regulation of cytosolic calcium ion concentration 16597920 Process
24514 GO:0007259 IDA involved_in receptor signaling pathway via JAK-STAT 11064147 Process
24514 GO:0007260 IMP involved_in tyrosine phosphorylation of STAT protein 15659221,17920330 Process
24514 GO:0008284 IMP involved_in positive regulation of cell population proliferation 16567515 Process
24514 GO:0008631 IMP involved_in intrinsic apoptotic signaling pathway in response to oxidative stress 15659221 Process
24514 GO:0009755 IDA involved_in hormone-mediated signaling pathway 11064147 Process
24514 GO:0010667 IMP involved_in negative regulation of cardiac muscle cell apoptotic process 23796350 Process
24514 GO:0014070 IEP involved_in response to organic cyclic compound 29486150 Process
24514 GO:0014075 IEP involved_in response to amine 29486150 Process
24514 GO:0022408 IMP involved_in negative regulation of cell-cell adhesion 15530849 Process
24514 GO:0030335 IMP involved_in positive regulation of cell migration 15530849 Process
24514 GO:0031103 IMP involved_in axon regeneration 15716400 Process
24514 GO:0031959 IMP involved_in mineralocorticoid receptor signaling pathway 15932931 Process
24514 GO:0032024 IMP involved_in positive regulation of insulin secretion 16597920 Process
24514 GO:0032516 IMP involved_in positive regulation of phosphoprotein phosphatase activity 17021051 Process
24514 GO:0032731 IMP involved_in positive regulation of interleukin-1 beta production 16934228 Process
24514 GO:0033194 IMP involved_in response to hydroperoxide 15659221 Process
24514 GO:0042307 IMP involved_in positive regulation of protein import into nucleus 15530849 Process
24514 GO:0043065 IMP involved_in positive regulation of apoptotic process 16269269 Process
24514 GO:0043066 IMP involved_in negative regulation of apoptotic process 22382519 Process
24514 GO:0043388 IMP involved_in positive regulation of DNA binding 15322111 Process
24514 GO:0043410 IMP involved_in positive regulation of MAPK cascade 16567515 Process
24514 GO:0043524 IMP involved_in negative regulation of neuron apoptotic process 12244045,23236988 Process
24514 GO:0045428 IGI involved_in regulation of nitric oxide biosynthetic process 16055727 Process
24514 GO:0045429 IMP involved_in positive regulation of nitric oxide biosynthetic process 12595539 Process
24514 GO:0045597 IMP involved_in positive regulation of cell differentiation 16514419 Process
24514 GO:0046777 IMP involved_in protein autophosphorylation 15530849 Process
24514 GO:0048008 IMP involved_in platelet-derived growth factor receptor signaling pathway 15948243 Process
24514 GO:0050804 IDA involved_in modulation of chemical synaptic transmission 22284190 Process
24514 GO:0050804 IMP involved_in modulation of chemical synaptic transmission 22284190 Process
24514 GO:0050867 IMP involved_in positive regulation of cell activation 15256805 Process
24514 GO:0051091 IMP involved_in positive regulation of DNA-binding transcription factor activity 15322111 Process
24514 GO:0051770 IDA involved_in positive regulation of nitric-oxide synthase biosynthetic process 11536325 Process
24514 GO:0060333 IDA involved_in type II interferon-mediated signaling pathway 11536325 Process
24514 GO:0060397 IDA involved_in growth hormone receptor signaling pathway via JAK-STAT 11244571 Process
24514 GO:1902728 IMP involved_in positive regulation of growth factor dependent skeletal muscle satellite cell proliferation 23869758 Process
24514 GO:1904037 IMP involved_in positive regulation of epithelial cell apoptotic process 22777122 Process
24514 GO:1904707 IMP involved_in positive regulation of vascular associated smooth muscle cell proliferation 23516544 Process
24514 GO:1905539 EXP involved_in regulation of postsynapse to nucleus signaling pathway 22284190 Process
24514 GO:1905539 IDA involved_in regulation of postsynapse to nucleus signaling pathway 22284190 Process