Gene Ontology

Gene Info

• Species: Rat (Rattus norvegicus)
• GeneID: 246294
• Symbol: Optn
• Description: optineurin

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
246294	GO:0001155	IPI	enables	TFIIIA-class transcription factor binding	10756201	Function
246294	GO:0042802	IPI	enables	identical protein binding	20161783	Function
246294	GO:0043130	IDA	enables	ubiquitin binding	21059646	Function

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
246294	GO:0001819	IMP	involved_in	positive regulation of cytokine production	28776281	Process
246294	GO:0003407	IEP	involved_in	neural retina development	17687037	Process
246294	GO:0007030	IMP	involved_in	Golgi organization	15837803,21896272	Process
246294	GO:0008284	IMP	involved_in	positive regulation of cell population proliferation	22194658	Process
246294	GO:0008285	IMP	involved_in	negative regulation of cell population proliferation	28776281	Process
246294	GO:0010628	IMP	involved_in	positive regulation of gene expression	22194658	Process
246294	GO:0043524	IMP	involved_in	negative regulation of neuron apoptotic process	22194658	Process
246294	GO:0043525	IMP	involved_in	positive regulation of neuron apoptotic process	25385380	Process
246294	GO:0070301	IEP	involved_in	cellular response to hydrogen peroxide	28776281	Process
246294	GO:0071356	IEP	involved_in	cellular response to tumor necrosis factor	28776281	Process
246294	GO:1905232	IEP	involved_in	cellular response to L-glutamate	28761318	Process
246294	GO:1990090	IEP	involved_in	cellular response to nerve growth factor stimulus	17663725	Process
246294	GO:2000179	IMP	involved_in	positive regulation of neural precursor cell proliferation	22194658	Process

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
246294	GO:0005794	IDA	located_in	Golgi apparatus	15837803	Component
246294	GO:0030424	IDA	located_in	axon	28761318	Component
246294	GO:0031410	IDA	located_in	cytoplasmic vesicle	15837803	Component
246294	GO:0043025	IDA	located_in	neuronal cell body	28761318	Component
246294	GO:0048471	IDA	located_in	perinuclear region of cytoplasm	28776281	Component