Gene Ontology

Gene Info

• Species: Rat (Rattus norvegicus)
• GeneID: 24842
• Symbol: Tp53
• Description: tumor protein p53

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
24842	GO:0000785	IDA	part_of	chromatin	15632413	Component
24842	GO:0005634	IDA	located_in	nucleus	17571083	Component
24842	GO:0005667	IDA	part_of	transcription regulator complex	15632413	Component
24842	GO:0016605	IDA	colocalizes_with	PML body	17289031	Component
24842	GO:0090575	IDA	part_of	RNA polymerase II transcription regulator complex	10329733	Component

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
24842	GO:0001221	IPI	enables	transcription coregulator binding	21792911	Function
24842	GO:0005515	IPI	enables	protein binding	8389468,11278372,12464630,15872011	Function
24842	GO:0031625	IPI	enables	ubiquitin protein ligase binding	16330492	Function
24842	GO:0043565	IDA	enables	sequence-specific DNA binding	15632413	Function
24842	GO:0044325	IPI	enables	transmembrane transporter binding	27013579	Function
24842	GO:0061629	IPI	enables	RNA polymerase II-specific DNA-binding transcription factor binding	10329733	Function
24842	GO:0097371	IPI	enables	MDM2/MDM4 family protein binding	23941874	Function

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
24842	GO:0002687	IMP	involved_in	positive regulation of leukocyte migration	18317410	Process
24842	GO:0006979	IEP	involved_in	response to oxidative stress	17600529	Process
24842	GO:0007283	IMP	involved_in	spermatogenesis	28834365	Process
24842	GO:0008285	IMP	acts_upstream_of	negative regulation of cell population proliferation	30514107	Process
24842	GO:0009410	IEP	involved_in	response to xenobiotic stimulus	18336558	Process
24842	GO:0009411	IEP	involved_in	response to UV	17724205	Process
24842	GO:0010035	IEP	involved_in	response to inorganic substance	18335527	Process
24842	GO:0010038	IEP	involved_in	response to metal ion	17466256	Process
24842	GO:0010165	IEP	involved_in	response to X-ray	17699727	Process
24842	GO:0010165	IMP	involved_in	response to X-ray	28834365	Process
24842	GO:0010224	IEP	involved_in	response to UV-B	22559303	Process
24842	GO:0010243	IEP	involved_in	response to organonitrogen compound	18311796	Process
24842	GO:0010628	IGI	involved_in	positive regulation of gene expression	23164821	Process
24842	GO:0014070	IEP	involved_in	response to organic cyclic compound	18093815	Process
24842	GO:0031000	IEP	involved_in	response to caffeine	16544096	Process
24842	GO:0032526	IEP	involved_in	response to retinoic acid	17962954	Process
24842	GO:0033552	IEP	involved_in	response to vitamin B3	17516866	Process
24842	GO:0034097	IEP	involved_in	response to cytokine	17651018	Process
24842	GO:0034605	IEP	involved_in	cellular response to heat	11295070	Process
24842	GO:0034614	IMP	involved_in	cellular response to reactive oxygen species	24817286	Process
24842	GO:0043065	IMP	involved_in	positive regulation of apoptotic process	16688778	Process
24842	GO:0043066	IMP	involved_in	negative regulation of apoptotic process	28834365	Process
24842	GO:0043200	IEP	involved_in	response to amino acid	17542038	Process
24842	GO:0045471	IEP	involved_in	response to ethanol	20961644	Process
24842	GO:0045787	IMP	involved_in	positive regulation of cell cycle	18026139	Process
24842	GO:0045892	IDA	involved_in	negative regulation of DNA-templated transcription	8389468	Process
24842	GO:0045944	IDA	involved_in	positive regulation of transcription by RNA polymerase II	11278372	Process
24842	GO:0048662	IMP	involved_in	negative regulation of smooth muscle cell proliferation	17659301	Process
24842	GO:0051453	IMP	involved_in	regulation of intracellular pH	16688778	Process
24842	GO:0051726	IMP	acts_upstream_of	regulation of cell cycle	30514107	Process
24842	GO:0055093	IEP	involved_in	response to hyperoxia	18337831	Process
24842	GO:0071401	IEP	involved_in	cellular response to triglyceride	27013579	Process
24842	GO:0071417	IEP	involved_in	cellular response to organonitrogen compound	11502571	Process
24842	GO:0071456	IEP	involved_in	cellular response to hypoxia	17289031	Process
24842	GO:0097190	IMP	involved_in	apoptotic signaling pathway	17998337	Process
24842	GO:2000279	IMP	involved_in	negative regulation of DNA biosynthetic process	11502571	Process
24842	GO:2001244	IMP	involved_in	positive regulation of intrinsic apoptotic signaling pathway	27031958	Process