Gene Ontology

Gene Info

• Species: Rat (Rattus norvegicus)
• GeneID: 24855
• Symbol: Tsc2
• Description: TSC complex subunit 2

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
24855	GO:0001933	IMP	involved_in	negative regulation of protein phosphorylation	18056446	Process
24855	GO:0008285	IMP	involved_in	negative regulation of cell population proliferation	17376623	Process
24855	GO:0010719	IMP	involved_in	negative regulation of epithelial to mesenchymal transition	20813961	Process
24855	GO:0010763	IMP	involved_in	positive regulation of fibroblast migration	20530489	Process
24855	GO:0010976	IMP	involved_in	positive regulation of neuron projection development	17376623	Process
24855	GO:0016242	IMP	involved_in	negative regulation of macroautophagy	24599401	Process
24855	GO:0030010	IMP	involved_in	establishment of cell polarity	20530489	Process
24855	GO:0030030	IGI	acts_upstream_of_or_within	cell projection organization	16286931	Process
24855	GO:0030030	IMP	acts_upstream_of_or_within	cell projection organization	16286931	Process
24855	GO:0030178	IDA	involved_in	negative regulation of Wnt signaling pathway	12511557	Process
24855	GO:0032007	IDA	involved_in	negative regulation of TOR signaling	12869586	Process
24855	GO:0034394	IMP	involved_in	protein localization to cell surface	20813961	Process
24855	GO:0035176	IMP	involved_in	social behavior	20927644	Process
24855	GO:0043407	IMP	involved_in	negative regulation of MAP kinase activity	14612383	Process
24855	GO:0045785	IMP	involved_in	positive regulation of cell adhesion	20813961	Process
24855	GO:0045792	IMP	acts_upstream_of_or_within	negative regulation of cell size	16286931	Process
24855	GO:0048147	IDA	involved_in	negative regulation of fibroblast proliferation	18056446	Process
24855	GO:0048550	IMP	involved_in	negative regulation of pinocytosis	9045618	Process
24855	GO:0050680	IDA	involved_in	negative regulation of epithelial cell proliferation	14612383	Process
24855	GO:0050771	IMP	involved_in	negative regulation of axonogenesis	18794346	Process
24855	GO:0060999	IMP	involved_in	positive regulation of dendritic spine development	16595860	Process
24855	GO:0099175	IDA	involved_in	regulation of postsynapse organization	24889507	Process
24855	GO:0099175	IMP	involved_in	regulation of postsynapse organization	24889507	Process
24855	GO:1905563	IMP	involved_in	negative regulation of vascular endothelial cell proliferation	11553313	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
24855	GO:0005096	IDA	enables	GTPase activator activity	12869586	Function
24855	GO:0005515	IPI	enables	protein binding	9045618,14559897	Function
24855	GO:0044877	IPI	enables	protein-containing complex binding	15093748	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
24855	GO:0005901	IDA	located_in	caveola	15093748	Component
24855	GO:0030425	IDA	located_in	dendrite	15525761	Component
24855	GO:0030426	IDA	located_in	growth cone	14559897	Component
24855	GO:0042995	IDA	located_in	cell projection	17376623	Component
24855	GO:0043025	IDA	located_in	neuronal cell body	15525761	Component
24855	GO:0048471	IDA	located_in	perinuclear region of cytoplasm	14559897	Component
24855	GO:0098978	IDA	is_active_in	glutamatergic synapse	24889507	Component
24855	GO:0098978	IMP	is_active_in	glutamatergic synapse	24889507	Component