Gene Ontology

Gene Info

  • Species: Rat (Rattus norvegicus)
  • GeneID: 24948
  • Symbol: Fmr1
  • Description: fragile X messenger ribonucleoprotein 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
24948 GO:0000340 IDA enables RNA 7-methylguanosine cap binding 25453757 Function
24948 GO:0003723 IDA enables RNA binding 12417734 Function
24948 GO:0003729 IPI enables mRNA binding 24338128 Function
24948 GO:0005515 IPI enables protein binding 24882364 Function
24948 GO:0019901 IPI enables protein kinase binding 23831253 Function
24948 GO:0019903 IDA enables protein phosphatase binding 23831253 Function
24948 GO:0019904 IDA enables protein domain specific binding 24882364 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
24948 GO:0001541 IEP involved_in ovarian follicle development 23401597 Process
24948 GO:0001934 IMP involved_in positive regulation of protein phosphorylation 22817682 Process
24948 GO:0002091 IMP involved_in negative regulation of receptor internalization 17881561 Process
24948 GO:0007215 IDA involved_in glutamate receptor signaling pathway 9144248 Process
24948 GO:0009416 IEP involved_in response to light stimulus 15564573 Process
24948 GO:0010628 IMP involved_in positive regulation of gene expression 22817682 Process
24948 GO:0010629 IMP involved_in negative regulation of gene expression 24338128 Process
24948 GO:0010955 IMP involved_in negative regulation of protein processing 22817682 Process
24948 GO:0014823 IEP involved_in response to activity 11001622 Process
24948 GO:0034698 IEP involved_in response to gonadotropin 23401597 Process
24948 GO:0035865 IEP involved_in cellular response to potassium ion 15028757 Process
24948 GO:0042220 IEP involved_in response to cocaine 24810662 Process
24948 GO:0043524 IMP involved_in negative regulation of neuron apoptotic process 22817682 Process
24948 GO:0045665 IMP involved_in negative regulation of neuron differentiation 24338128 Process
24948 GO:0046928 IMP involved_in regulation of neurotransmitter secretion 24709664 Process
24948 GO:0048170 IMP involved_in positive regulation of long-term neuronal synaptic plasticity 28894415 Process
24948 GO:0050806 IMP involved_in positive regulation of synaptic transmission 28894415 Process
24948 GO:0050974 IEP involved_in detection of mechanical stimulus involved in sensory perception 12591163 Process
24948 GO:0051602 IEP involved_in response to electrical stimulus 10686356 Process
24948 GO:0070555 IEP involved_in response to interleukin-1 10587350 Process
24948 GO:0098908 IMP involved_in regulation of neuronal action potential 27465362 Process
24948 GO:0099577 IDA involved_in regulation of translation at presynapse, modulating synaptic transmission 24709664 Process
24948 GO:0099577 IMP involved_in regulation of translation at presynapse, modulating synaptic transmission 24709664 Process
24948 GO:1900273 IMP involved_in positive regulation of long-term synaptic potentiation 28894415 Process
24948 GO:1900454 IMP involved_in positive regulation of long-term synaptic depression 28894415 Process
24948 GO:1901386 IMP involved_in negative regulation of voltage-gated calcium channel activity 24709664 Process
24948 GO:1905232 IEP involved_in cellular response to L-glutamate 22817682 Process
24948 GO:2000301 IMP involved_in negative regulation of synaptic vesicle exocytosis 24709664 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
24948 GO:0005634 IDA located_in nucleus 9030614 Component
24948 GO:0005654 IDA located_in nucleoplasm 9030614 Component
24948 GO:0005844 IDA part_of polysome 9144248,14613971 Component
24948 GO:0010494 IDA located_in cytoplasmic stress granule 16510718,16919243 Component
24948 GO:0014069 IDA located_in postsynaptic density 9144248 Component
24948 GO:0015630 IDA located_in microtubule cytoskeleton 17881655 Component
24948 GO:0030424 IDA located_in axon 16809002 Component
24948 GO:0030425 IDA located_in dendrite 9030614,9144248,15028757,15564573,16571602 Component
24948 GO:0030426 IDA located_in growth cone 16098134 Component
24948 GO:0036464 IDA located_in cytoplasmic ribonucleoprotein granule 16098134 Component
24948 GO:0043005 IDA located_in neuron projection 24709664 Component
24948 GO:0043025 IDA located_in neuronal cell body 15028757 Component
24948 GO:0043195 IDA located_in terminal bouton 15028757 Component
24948 GO:0043197 IDA located_in dendritic spine 9030614,9144248 Component
24948 GO:0043204 IDA located_in perikaryon 9030614,9144248,12112448,14613971,16571602,24709664..... Component
24948 GO:0043679 IDA located_in axon terminus 9030614 Component
24948 GO:0044297 IDA located_in cell body 17881655 Component
24948 GO:0044326 IDA located_in dendritic spine neck 15028757 Component
24948 GO:0044327 IDA located_in dendritic spine head 15028757 Component
24948 GO:0048471 IDA located_in perinuclear region of cytoplasm 23831253 Component
24948 GO:0071598 IDA located_in neuronal ribonucleoprotein granule 17881655 Component
24948 GO:0097386 IDA located_in glial cell projection 14613971 Component
24948 GO:0097444 IDA located_in spine apparatus 9030614 Component
24948 GO:0098685 IDA is_active_in Schaffer collateral - CA1 synapse 9144248 Component
24948 GO:0098978 IDA is_active_in glutamatergic synapse 9144248,24709664 Component
24948 GO:0098978 IMP is_active_in glutamatergic synapse 24709664 Component
24948 GO:0099524 IDA is_active_in postsynaptic cytosol 9144248 Component
24948 GO:1902737 IDA located_in dendritic filopodium 15028757,16098134 Component
24948 GO:1990635 IDA located_in proximal dendrite 12112448 Component