Gene Ontology

Gene Info

  • Species: Rat (Rattus norvegicus)
  • GeneID: 24954
  • Symbol: Insr
  • Description: insulin receptor

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
24954 GO:0000380 IEP involved_in alternative mRNA splicing, via spliceosome 23633480 Process
24954 GO:0001666 IEP involved_in response to hypoxia 25352008 Process
24954 GO:0001889 IEP involved_in liver development 6364984 Process
24954 GO:0001933 IMP involved_in negative regulation of protein phosphorylation 17585961 Process
24954 GO:0006111 IEP involved_in regulation of gluconeogenesis 29896241 Process
24954 GO:0006468 IDA involved_in protein phosphorylation 12891559 Process
24954 GO:0006468 IEP involved_in protein phosphorylation 22546076 Process
24954 GO:0006898 IMP involved_in receptor-mediated endocytosis 19406747 Process
24954 GO:0008286 IDA involved_in insulin receptor signaling pathway 12891559 Process
24954 GO:0008286 IEP involved_in insulin receptor signaling pathway 15520221,26300412,29896241 Process
24954 GO:0008286 IMP involved_in insulin receptor signaling pathway 12850498,19406747 Process
24954 GO:0009725 IEP involved_in response to hormone 18672341 Process
24954 GO:0009749 IEP involved_in response to glucose 12435589 Process
24954 GO:0010033 IEP involved_in response to organic substance 30717198 Process
24954 GO:0010042 IEP involved_in response to manganese ion 6368536 Process
24954 GO:0010310 IDA involved_in regulation of hydrogen peroxide metabolic process 17919343 Process
24954 GO:0010560 IMP involved_in positive regulation of glycoprotein biosynthetic process 19049803 Process
24954 GO:0010629 IMP involved_in negative regulation of gene expression 17585961 Process
24954 GO:0014823 IEP involved_in response to activity 17603294 Process
24954 GO:0018108 IMP involved_in peptidyl-tyrosine phosphorylation 12850498 Process
24954 GO:0021549 IEP involved_in cerebellum development 23397157 Process
24954 GO:0021766 IEP involved_in hippocampus development 22042446 Process
24954 GO:0031667 IDA involved_in response to nutrient levels 15520221 Process
24954 GO:0031667 IEP involved_in response to nutrient levels 19088253,25160038,26300412 Process
24954 GO:0032094 IEP involved_in response to food 19880292 Process
24954 GO:0032355 IEP involved_in response to estradiol 17931855 Process
24954 GO:0032410 IMP involved_in negative regulation of transporter activity 19049803 Process
24954 GO:0032868 IEP involved_in response to insulin 1280238,12435589,18923314 Process
24954 GO:0033280 IEP involved_in response to vitamin D 18638371 Process
24954 GO:0033574 IEP involved_in response to testosterone 17673259 Process
24954 GO:0034224 IEP involved_in cellular response to zinc ion starvation 21893222 Process
24954 GO:0034612 IMP involved_in response to tumor necrosis factor 17761893 Process
24954 GO:0042327 IDA involved_in positive regulation of phosphorylation 12435589 Process
24954 GO:0042594 IEP involved_in response to starvation 1280238 Process
24954 GO:0043243 IGI involved_in positive regulation of protein-containing complex disassembly 19406747 Process
24954 GO:0045444 IEP involved_in fat cell differentiation 17286602 Process
24954 GO:0045471 IEP involved_in response to ethanol 19185210 Process
24954 GO:0045719 IEP involved_in negative regulation of glycogen biosynthetic process 26300412 Process
24954 GO:0046777 IDA involved_in protein autophosphorylation 2180315,3275643,12891559,17919343 Process
24954 GO:0046777 IMP involved_in protein autophosphorylation 12850498 Process
24954 GO:0051384 IEP involved_in response to glucocorticoid 18401942 Process
24954 GO:0097062 IGI involved_in dendritic spine maintenance 19406747 Process
24954 GO:0097242 IMP involved_in amyloid-beta clearance 19406747 Process
24954 GO:0097421 IEP involved_in liver regeneration 23633480 Process
24954 GO:1902438 IEP involved_in response to vanadate(3-) 2180315 Process
24954 GO:1904638 IEP involved_in response to resveratrol 25352008 Process
24954 GO:1990402 IEP involved_in embryonic liver development 1448116 Process
24954 GO:1990535 IGI involved_in neuron projection maintenance 19188609 Process
24954 GO:2000252 IMP involved_in negative regulation of feeding behavior 12021765 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
24954 GO:0004672 IDA enables protein kinase activity 17429032 Function
24954 GO:0004713 IDA enables protein tyrosine kinase activity 2180315,18657188 Function
24954 GO:0005009 IDA enables insulin receptor activity 3275643,12891559,17023527 Function
24954 GO:0005009 IMP enables insulin receptor activity 12850498,17023527 Function
24954 GO:0005515 IPI enables protein binding 8912646,15665515,22173225,25687571 Function
24954 GO:0019901 IPI enables protein kinase binding 17318260,19952103 Function
24954 GO:0019903 IMP enables protein phosphatase binding 12850498 Function
24954 GO:0019904 IPI enables protein domain specific binding 9748281 Function
24954 GO:0031405 IPI enables lipoic acid binding 17274632 Function
24954 GO:0038024 IMP enables cargo receptor activity 19406747 Function
24954 GO:0043423 IDA enables 3-phosphoinositide-dependent protein kinase binding 16314505 Function
24954 GO:0043559 IDA enables insulin binding 2180315,3275643,17023527 Function
24954 GO:0043559 IMP enables insulin binding 12850498,17023527 Function
24954 GO:0043560 IMP enables insulin receptor substrate binding 12850498 Function
24954 GO:0044877 IPI enables protein-containing complex binding 3516142 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
24954 GO:0005768 IDA located_in endosome 15665515 Component
24954 GO:0009897 IDA located_in external side of plasma membrane 19188609 Component
24954 GO:0030425 IDA colocalizes_with dendrite 19406747 Component
24954 GO:0032590 IDA located_in dendrite membrane 19188609 Component
24954 GO:0032809 IDA located_in neuronal cell body membrane 19188609 Component
24954 GO:0043025 IDA colocalizes_with neuronal cell body 19406747 Component
24954 GO:0043025 IDA located_in neuronal cell body 12021765,18479783 Component
24954 GO:0044297 IDA colocalizes_with cell body 19406747 Component
24954 GO:0060417 IDA located_in yolk 1448116 Component