Gene Ontology

Gene Info

• Species: Fission yeast (Schizosaccharomyces pombe)
• GeneID: 2542757
• Symbol: mre11
• Description: Mre11 nuclease

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
2542757	GO:0000723	IGI	involved_in	telomere maintenance	12861005	Process
2542757	GO:0000724	IMP	involved_in	double-strand break repair via homologous recombination	12628934	Process
2542757	GO:0000729	IMP	involved_in	DNA double-strand break processing	19139281,19752195,19911044,21931565,23080121	Process
2542757	GO:0006302	IMP	involved_in	double-strand break repair	7885834	Process
2542757	GO:0006303	IGI	involved_in	double-strand break repair via nonhomologous end joining	23188080	Process
2542757	GO:0006303	IMP	involved_in	double-strand break repair via nonhomologous end joining	10373582,23188080	Process
2542757	GO:0007131	IMP	involved_in	reciprocal meiotic recombination	7885834	Process
2542757	GO:0031573	IMP	involved_in	mitotic intra-S DNA damage checkpoint signaling	12944482	Process
2542757	GO:0042138	IMP	involved_in	meiotic DNA double-strand break formation	15654094	Process
2542757	GO:1990918	IMP	involved_in	double-strand break repair involved in meiotic recombination	15238514	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
2542757	GO:0004518	IDA	enables	nuclease activity	22705791	Function
2542757	GO:0005515	IPI	enables	protein binding	12944481,12944482,18854158,21441914,22705791,23080121.....	Function
2542757	GO:0030145	IDA	enables	manganese ion binding	22705791	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
2542757	GO:0030870	IDA	part_of	Mre11 complex	22705791	Component
2542757	GO:0035861	IDA	is_active_in	site of double-strand break	17936710,19804755,21931565,23080121,29851556	Component
2542757	GO:0140445	IDA	is_active_in	chromosome, telomeric repeat region	12196391,12861005	Component