Gene Ontology

Gene Info

  • Species: Rat (Rattus norvegicus)
  • GeneID: 25622
  • Symbol: Ptpn11
  • Description: protein tyrosine phosphatase, non-receptor type 11

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
25622 GO:0004725 IDA enables protein tyrosine phosphatase activity 7512964,7711057,15272025,15378208 Function
25622 GO:0005158 IDA enables insulin receptor binding 7711057 Function
25622 GO:0005515 IPI enables protein binding 7545675,8810330,8912646,12959980,15128762,31585087 Function
25622 GO:0019904 IPI enables protein domain specific binding 10973965 Function
25622 GO:0030971 IPI enables receptor tyrosine kinase binding 15115663 Function
25622 GO:0031748 IPI enables D1 dopamine receptor binding 23328768 Function
25622 GO:0043274 IDA enables phospholipase binding 16814162 Function
25622 GO:0043560 IPI enables insulin receptor substrate binding 12891559 Function
25622 GO:0050839 IPI enables cell adhesion molecule binding 9388260 Function
25622 GO:1990782 IPI enables protein tyrosine kinase binding 16690621 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
25622 GO:0006470 IDA involved_in protein dephosphorylation 7711057,15272025 Process
25622 GO:0048659 IEP involved_in smooth muscle cell proliferation 12117720 Process
25622 GO:0051894 IMP involved_in positive regulation of focal adhesion assembly 16905534 Process
25622 GO:0070301 IEP involved_in cellular response to hydrogen peroxide 19348936 Process
25622 GO:0071260 IPI involved_in cellular response to mechanical stimulus 18757826 Process
25622 GO:1904385 IEP involved_in cellular response to angiotensin 9139682 Process
25622 GO:1990314 IEP involved_in cellular response to insulin-like growth factor stimulus 9139682 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
25622 GO:0032991 IDA part_of protein-containing complex 10973965 Component
25622 GO:0044853 IDA located_in plasma membrane raft 19348936 Component