Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 25978
  • Symbol: CHMP2B
  • Description: charged multivesicular body protein 2B

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
25978 GO:0000421 IDA located_in autophagosome membrane 17984323 Component
25978 GO:0000776 IDA located_in kinetochore 26040712 Component
25978 GO:0000815 IDA part_of ESCRT III complex 24878737 Component
25978 GO:0005643 IDA part_of nuclear pore 26040713 Component
25978 GO:0005737 IDA located_in cytoplasm 24878737,25468996 Component
25978 GO:0005764 IDA colocalizes_with lysosome 16041373 Component
25978 GO:0005765 IDA located_in lysosomal membrane 17984323 Component
25978 GO:0005768 IDA colocalizes_with endosome 24878737 Component
25978 GO:0005770 IDA colocalizes_with late endosome 16041373 Component
25978 GO:0005828 IDA located_in kinetochore microtubule 26040712 Component
25978 GO:0005829 IDA located_in cytosol 16041373 Component
25978 GO:0005886 IDA colocalizes_with plasma membrane 24878737 Component
25978 GO:0005886 IDA located_in plasma membrane 24878737 Component
25978 GO:0030496 IDA located_in midbody 26040712 Component
25978 GO:0032585 IDA located_in multivesicular body membrane 16554368 Component
25978 GO:0070062 HDA located_in extracellular exosome 19056867,23533145 Component
25978 GO:1904930 IDA located_in amphisome membrane 17984323 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
25978 GO:0001778 IDA involved_in plasma membrane repair 24482116 Process
25978 GO:0006914 IMP involved_in autophagy 17984323 Process
25978 GO:0006997 IMP involved_in nucleus organization 20616062 Process
25978 GO:0007032 IMP involved_in endosome organization 16041373 Process
25978 GO:0007080 IMP involved_in mitotic metaphase plate congression 20616062 Process
25978 GO:0010824 IMP involved_in regulation of centrosome duplication 20616062 Process
25978 GO:0019076 IGI involved_in viral release from host cell 23051622 Process
25978 GO:0019076 IMP involved_in viral release from host cell 23051622 Process
25978 GO:0031468 IMP involved_in nuclear membrane reassembly 26040713 Process
25978 GO:0039702 IDA involved_in viral budding via host ESCRT complex 24878737 Process
25978 GO:0039702 IGI involved_in viral budding via host ESCRT complex 24107264 Process
25978 GO:0039702 IMP involved_in viral budding via host ESCRT complex 23051622 Process
25978 GO:0043162 IDA involved_in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 17984323 Process
25978 GO:0046761 IDA involved_in viral budding from plasma membrane 24878737 Process
25978 GO:0050890 IMP involved_in cognition 16041373 Process
25978 GO:0061952 IMP involved_in midbody abscission 20616062 Process
25978 GO:0070050 IMP involved_in neuron cellular homeostasis 16041373,16807408 Process
25978 GO:0071985 IDA involved_in multivesicular body sorting pathway 16554368 Process
25978 GO:0097352 IMP involved_in autophagosome maturation 17984323 Process
25978 GO:1901673 IMP involved_in regulation of mitotic spindle assembly 20616062 Process
25978 GO:1902774 IMP involved_in late endosome to lysosome transport 17984323 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
25978 GO:0005515 IPI enables protein binding 16730941,17683935,21044950,21975012,22046132,23051622,26496610..... Function
25978 GO:0019904 IPI enables protein domain specific binding 17928862 Function
25978 GO:0045296 HDA enables cadherin binding 25468996 Function