Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 26413
  • Symbol: Mapk1
  • Description: mitogen-activated protein kinase 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
26413 GO:0000165 IDA acts_upstream_of_or_within MAPK cascade 8626447,9064344,9254656 Process
26413 GO:0006468 IDA acts_upstream_of_or_within protein phosphorylation 11841548,14744933,15284227 Process
26413 GO:0006468 IMP acts_upstream_of_or_within protein phosphorylation 15896720 Process
26413 GO:0006974 IDA acts_upstream_of_or_within DNA damage response 15383658 Process
26413 GO:0007507 IMP acts_upstream_of_or_within heart development 18952847 Process
26413 GO:0008286 IDA involved_in insulin receptor signaling pathway 20056832 Process
26413 GO:0009887 IDA acts_upstream_of_or_within animal organ morphogenesis 11684667 Process
26413 GO:0014032 IGI acts_upstream_of_or_within neural crest cell development 18952847 Process
26413 GO:0018105 IDA acts_upstream_of_or_within peptidyl-serine phosphorylation 18084034 Process
26413 GO:0018105 IDA involved_in peptidyl-serine phosphorylation 11854404 Process
26413 GO:0018105 IMP acts_upstream_of_or_within peptidyl-serine phosphorylation 18084034 Process
26413 GO:0018107 IDA involved_in peptidyl-threonine phosphorylation 11854404 Process
26413 GO:0019858 IDA acts_upstream_of_or_within cytosine metabolic process 15284227 Process
26413 GO:0030278 IGI acts_upstream_of_or_within regulation of ossification 20053668 Process
26413 GO:0030641 IMP acts_upstream_of_or_within regulation of cellular pH 26375174 Process
26413 GO:0030878 IGI acts_upstream_of_or_within thyroid gland development 18952847 Process
26413 GO:0031663 IDA acts_upstream_of_or_within lipopolysaccharide-mediated signaling pathway 12872135 Process
26413 GO:0032496 IDA acts_upstream_of_or_within response to lipopolysaccharide 12872135 Process
26413 GO:0033598 IDA acts_upstream_of_or_within mammary gland epithelial cell proliferation 18604197 Process
26413 GO:0035094 IGI involved_in response to nicotine 11404397 Process
26413 GO:0042473 IGI acts_upstream_of_or_within outer ear morphogenesis 18952847 Process
26413 GO:0043330 IDA acts_upstream_of_or_within response to exogenous dsRNA 12872135 Process
26413 GO:0045596 IGI acts_upstream_of_or_within negative regulation of cell differentiation 14970190 Process
26413 GO:0048009 IDA involved_in insulin-like growth factor receptor signaling pathway 14997210,24381169 Process
26413 GO:0048538 IGI acts_upstream_of_or_within thymus development 18952847 Process
26413 GO:0050852 IDA acts_upstream_of_or_within T cell receptor signaling pathway 9064344 Process
26413 GO:0050853 IDA acts_upstream_of_or_within B cell receptor signaling pathway 9254656 Process
26413 GO:0060020 IGI acts_upstream_of_or_within Bergmann glial cell differentiation 24431450 Process
26413 GO:0060291 IGI acts_upstream_of_or_within long-term synaptic potentiation 20661302 Process
26413 GO:0060324 IGI acts_upstream_of_or_within face development 18952847 Process
26413 GO:0060324 IMP acts_upstream_of_or_within face development 18952847 Process
26413 GO:0060425 IGI acts_upstream_of_or_within lung morphogenesis 25100655 Process
26413 GO:0060440 IGI acts_upstream_of_or_within trachea formation 25100655 Process
26413 GO:0060716 IMP acts_upstream_of_or_within labyrinthine layer blood vessel development 14622137 Process
26413 GO:0061308 IGI acts_upstream_of_or_within cardiac neural crest cell development involved in heart development 18952847 Process
26413 GO:0070371 IGI acts_upstream_of_or_within ERK1 and ERK2 cascade 19047410 Process
26413 GO:0071356 IGI acts_upstream_of_or_within cellular response to tumor necrosis factor 24349514 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
26413 GO:0001784 IMP enables phosphotyrosine residue binding 14636584 Function
26413 GO:0004672 IDA enables protein kinase activity 14744933 Function
26413 GO:0004674 IDA enables protein serine/threonine kinase activity 11854404,26240334 Function
26413 GO:0004707 IDA enables MAP kinase activity 1659995,8626447,9064344,9254656,12223545,15314156,15896720,180..... Function
26413 GO:0004707 IMP enables MAP kinase activity 11841548,18084034 Function
26413 GO:0004708 IMP enables MAP kinase kinase activity 26375174 Function
26413 GO:0005515 IPI enables protein binding 10419510,15102471,15196959,15284227,15537391,15544353,16148006..... Function
26413 GO:0008353 IDA enables RNA polymerase II CTD heptapeptide repeat kinase activity 12721286 Function
26413 GO:0016301 IDA enables kinase activity 12808090,15284227 Function
26413 GO:0019902 IPI enables phosphatase binding 8221888 Function
26413 GO:0042802 IPI enables identical protein binding 26267534 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
26413 GO:0005634 IDA located_in nucleus 11726647,12925581,16251435,20554783 Component
26413 GO:0005737 IDA located_in cytoplasm 11726647,12223545,12925581,20554783 Component
26413 GO:0005739 IDA located_in mitochondrion 11884367 Component
26413 GO:0005829 IDA located_in cytosol 9447983,11884367,22451653 Component
26413 GO:0031143 IDA located_in pseudopodium 12821670 Component