Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 2645
• Symbol: GCK
• Description: glucokinase

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
2645	GO:0004340	IDA	enables	glucokinase activity	8446612,12941786,16173921,22611063	Function
2645	GO:0004340	IMP	enables	glucokinase activity	18322640,19146401	Function
2645	GO:0005515	IPI	enables	protein binding	11522786,16173921,32296183	Function
2645	GO:0005524	IDA	enables	ATP binding	8446612,12941786,16173921	Function
2645	GO:0005536	IDA	enables	glucose binding	8446612,12941786,16173921	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
2645	GO:0005829	IDA	located_in	cytosol		Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
2645	GO:0006007	IMP	involved_in	glucose catabolic process	12941786	Process
2645	GO:0032024	IMP	involved_in	positive regulation of insulin secretion	8132752,8878425	Process
2645	GO:0042593	IMP	involved_in	glucose homeostasis	8132752,20668700	Process
2645	GO:0045721	IMP	involved_in	negative regulation of gluconeogenesis	8878425	Process
2645	GO:0045725	IMP	involved_in	positive regulation of glycogen biosynthetic process	8878425	Process
2645	GO:0050796	IMP	involved_in	regulation of insulin secretion	20668700	Process
2645	GO:0051156	IMP	involved_in	glucose 6-phosphate metabolic process	18322640,19146401	Process