Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 27183
  • Symbol: VPS4A
  • Description: vacuolar protein sorting 4 homolog A

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
27183 GO:0000922 IDA located_in spindle pole 20616062 Component
27183 GO:0005634 IDA located_in nucleus 20616062 Component
27183 GO:0005737 IDA located_in cytoplasm 11563910,15075231,20616062 Component
27183 GO:0005764 IDA located_in lysosome Component
27183 GO:0005768 IDA located_in endosome 17940959 Component
27183 GO:0005769 IDA located_in early endosome 15075231 Component
27183 GO:0005770 IDA located_in late endosome 15075231 Component
27183 GO:0005774 IDA located_in vacuolar membrane Component
27183 GO:0005813 IDA located_in centrosome 20616062 Component
27183 GO:0005829 IDA located_in cytosol Component
27183 GO:0005886 IDA located_in plasma membrane 17940959 Component
27183 GO:0010008 IMP located_in endosome membrane 18606141 Component
27183 GO:0030496 IDA located_in midbody 17853893,19129479,24814515 Component
27183 GO:0048471 IDA located_in perinuclear region of cytoplasm 11563910 Component
27183 GO:0070062 HDA located_in extracellular exosome 19199708,23533145 Component
27183 GO:0090543 IDA located_in Flemming body 20616062 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
27183 GO:0005515 IPI enables protein binding 11559748,11563910,14505570,14519844,16174732,16730941,17928862..... Function
27183 GO:0005524 IMP enables ATP binding Function
27183 GO:0016887 IMP enables ATP hydrolysis activity Function
27183 GO:0044877 IPI enables protein-containing complex binding 18606141 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
27183 GO:0006622 IMP involved_in protein targeting to lysosome 16973552 Process
27183 GO:0006900 IMP involved_in vesicle budding from membrane 15075231 Process
27183 GO:0006997 IMP involved_in nucleus organization 20616062 Process
27183 GO:0007080 IMP involved_in mitotic metaphase plate congression 20616062 Process
27183 GO:0009838 IMP involved_in abscission 24814515 Process
27183 GO:0016192 IDA involved_in vesicle-mediated transport 11563910 Process
27183 GO:0016197 IMP involved_in endosomal transport 11559748 Process
27183 GO:0019076 IMP involved_in viral release from host cell 11595185 Process
27183 GO:0032367 IMP involved_in intracellular cholesterol transport Process
27183 GO:0032466 IMP involved_in negative regulation of cytokinesis 24814515 Process
27183 GO:0032880 IMP involved_in regulation of protein localization 18005716 Process
27183 GO:0034058 IMP involved_in endosomal vesicle fusion 15075231 Process
27183 GO:0039702 IGI involved_in viral budding via host ESCRT complex 24107264 Process
27183 GO:0043162 IMP involved_in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 22547407 Process
27183 GO:0044878 IMP involved_in mitotic cytokinesis checkpoint signaling 24814515 Process
27183 GO:0046761 IMP involved_in viral budding from plasma membrane 16193069,17940959 Process
27183 GO:0051301 IDA involved_in cell division 17853893 Process
27183 GO:0061952 IMP involved_in midbody abscission 20616062 Process
27183 GO:0072319 IMP involved_in vesicle uncoating 15075231 Process
27183 GO:0090611 IMP involved_in ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway 22547407 Process
27183 GO:1903076 IMP involved_in regulation of protein localization to plasma membrane 24878737 Process
27183 GO:1903543 IMP involved_in positive regulation of exosomal secretion 22660413 Process
27183 GO:1903774 IMP involved_in positive regulation of viral budding via host ESCRT complex 24878737 Process