Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 274
  • Symbol: BIN1
  • Description: bridging integrator 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
274 GO:0000122 IDA involved_in negative regulation of transcription by RNA polymerase II 10412034 Process
274 GO:0006997 IMP involved_in nucleus organization 26506308 Process
274 GO:0008333 IMP involved_in endosome to lysosome transport 27179792 Process
274 GO:0010564 IDA involved_in regulation of cell cycle process 8782822 Process
274 GO:0033292 IDA involved_in T-tubule organization 24755653 Process
274 GO:0043065 IDA involved_in positive regulation of apoptotic process 16530520 Process
274 GO:0043065 IMP involved_in positive regulation of apoptotic process 10412034 Process
274 GO:0045664 IMP involved_in regulation of neuron differentiation 10412034 Process
274 GO:0048711 IMP involved_in positive regulation of astrocyte differentiation 10412034 Process
274 GO:0060988 IMP involved_in lipid tube assembly 19004523 Process
274 GO:1902430 IMP involved_in negative regulation of amyloid-beta formation 27179792 Process
274 GO:1902960 IMP involved_in negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process 27179792 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
274 GO:0002020 IPI enables protease binding 27179792 Function
274 GO:0005515 IPI enables protein binding 10903846,12604805,12668730,16275660,16530520,17676042,18647389..... Function
274 GO:0019828 IMP enables aspartic-type endopeptidase inhibitor activity 27179792 Function
274 GO:0042802 IPI enables identical protein binding 23917616,31413325 Function
274 GO:0048156 IPI enables tau protein binding 23399914,25051234 Function
274 GO:0051015 IDA enables actin filament binding 26506308 Function
274 GO:0051087 IPI enables protein-folding chaperone binding 25051234 Function
274 GO:0070063 IPI enables RNA polymerase binding 16530520 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
274 GO:0005634 IDA located_in nucleus 8782822,25051234 Component
274 GO:0005737 IDA located_in cytoplasm 25051234 Component
274 GO:0005829 IDA located_in cytosol Component
274 GO:0005856 IDA colocalizes_with cytoskeleton 25051234 Component
274 GO:0016020 IDA located_in membrane 16530520,25051234 Component
274 GO:0030424 IDA located_in axon 23399914 Component
274 GO:0060987 IMP part_of lipid tube 19004523 Component
274 GO:0090571 IPI part_of RNA polymerase II transcription repressor complex 15992821 Component