Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 27403
  • Symbol: Abca7
  • Description: ATP-binding cassette, sub-family A member 7

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
27403 GO:0001891 IDA located_in phagocytic cup 16908670 Component
27403 GO:0005622 IDA located_in intracellular anatomical structure 15520449 Component
27403 GO:0005737 IDA located_in cytoplasm 27472885 Component
27403 GO:0009986 IDA located_in cell surface 12917409,20495215 Component
27403 GO:0016324 IDA located_in apical plasma membrane 15520449 Component
27403 GO:0032587 IDA located_in ruffle membrane 16908670 Component
27403 GO:0097386 IDA located_in glial cell projection 27472885 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
27403 GO:0005515 IPI enables protein binding 12917409 Function
27403 GO:0005548 IDA enables phospholipid transporter activity 15520449 Function
27403 GO:0034188 IDA enables apolipoprotein A-I receptor activity 12917409 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
27403 GO:0007613 IMP involved_in memory 23467355 Process
27403 GO:0008542 IMP involved_in visual learning 27030769 Process
27403 GO:0010875 IDA involved_in positive regulation of cholesterol efflux 18429932 Process
27403 GO:0015914 IDA acts_upstream_of_or_within phospholipid transport 15520449 Process
27403 GO:0018149 IDA involved_in peptide cross-linking 12917409 Process
27403 GO:0019216 IMP involved_in regulation of lipid metabolic process 27030769 Process
27403 GO:0033344 IMP involved_in cholesterol efflux 27472885 Process
27403 GO:0033700 IDA acts_upstream_of_or_within phospholipid efflux 15520449 Process
27403 GO:0033700 IMP involved_in phospholipid efflux 27472885 Process
27403 GO:0034205 IMP involved_in amyloid-beta formation 26260791 Process
27403 GO:0034504 IDA involved_in protein localization to nucleus 18429932 Process
27403 GO:0038027 IDA involved_in apolipoprotein A-I-mediated signaling pathway 12917409 Process
27403 GO:0038027 IMP involved_in apolipoprotein A-I-mediated signaling pathway 20495215 Process
27403 GO:0042985 IDA involved_in negative regulation of amyloid precursor protein biosynthetic process 18429932 Process
27403 GO:0043409 IMP involved_in negative regulation of MAPK cascade 27030769 Process
27403 GO:0044857 IMP involved_in plasma membrane raft organization 28091533 Process
27403 GO:0045806 IMP involved_in negative regulation of endocytosis 26260791 Process
27403 GO:0050766 IMP involved_in positive regulation of phagocytosis 20495215,27472885 Process
27403 GO:0070374 IMP involved_in positive regulation of ERK1 and ERK2 cascade 16908670 Process
27403 GO:0150094 IMP involved_in amyloid-beta clearance by cellular catabolic process 27472885 Process
27403 GO:1900223 IMP involved_in positive regulation of amyloid-beta clearance 23467355 Process
27403 GO:1901076 IMP involved_in positive regulation of engulfment of apoptotic cell 16908670 Process
27403 GO:1902430 IDA involved_in negative regulation of amyloid-beta formation 18429932 Process
27403 GO:1902430 IMP involved_in negative regulation of amyloid-beta formation 23467355,27030769 Process
27403 GO:1902995 IDA involved_in positive regulation of phospholipid efflux 12917409 Process
27403 GO:1903898 IMP involved_in negative regulation of PERK-mediated unfolded protein response 27030769 Process
27403 GO:2000010 IMP involved_in positive regulation of protein localization to cell surface 28091533 Process