Gene Ontology

Gene Info

• Species: Fly (Drosophila melanogaster)
• GeneID: 2768677
• Symbol: p53
• Description: p53

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
2768677	GO:0000976	IDA	enables	transcription cis-regulatory region binding	25453105	Function
2768677	GO:0001097	IPI	enables	TFIIH-class transcription factor complex binding	23549790	Function
2768677	GO:0005515	IPI	enables	protein binding	17170702,17933869	Function
2768677	GO:0008134	IPI	enables	transcription factor binding	18549481	Function
2768677	GO:0031624	IPI	enables	ubiquitin conjugating enzyme binding	21205821	Function
2768677	GO:0031625	IPI	enables	ubiquitin protein ligase binding	17170702	Function
2768677	GO:0061629	IPI	enables	RNA polymerase II-specific DNA-binding transcription factor binding	18549481	Function
2768677	GO:1990841	IDA	enables	promoter-specific chromatin binding	24265704	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
2768677	GO:0005634	HDA	located_in	nucleus	26896675	Component
2768677	GO:0005634	IDA	located_in	nucleus	19153663	Component
2768677	GO:0005634	IMP	located_in	nucleus	26996664	Component
2768677	GO:0010369	IDA	colocalizes_with	chromocenter	25882045	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
2768677	GO:0006282	IMP	involved_in	regulation of DNA repair	14729967	Process
2768677	GO:0006357	IMP	involved_in	regulation of transcription by RNA polymerase II	25211335	Process
2768677	GO:0006915	IMP	involved_in	apoptotic process	12672954,16079158	Process
2768677	GO:0006919	IMP	involved_in	activation of cysteine-type endopeptidase activity involved in apoptotic process	17310982	Process
2768677	GO:0006974	IMP	involved_in	DNA damage response	14532134	Process
2768677	GO:0007131	IMP	involved_in	reciprocal meiotic recombination	20522776	Process
2768677	GO:0007405	IMP	involved_in	neuroblast proliferation	22140513	Process
2768677	GO:0008340	IMP	involved_in	determination of adult lifespan	16303568,17686972	Process
2768677	GO:0008630	IMP	involved_in	intrinsic apoptotic signaling pathway in response to DNA damage	18688282	Process
2768677	GO:0009267	IMP	involved_in	cellular response to starvation	18794330,25393288	Process
2768677	GO:0009314	IMP	involved_in	response to radiation	12672954	Process
2768677	GO:0009411	IMP	involved_in	response to UV	16412438	Process
2768677	GO:0010212	IMP	involved_in	response to ionizing radiation	17933869,24240233,25882045	Process
2768677	GO:0010628	IMP	involved_in	positive regulation of gene expression	26996664	Process
2768677	GO:0014016	IMP	involved_in	neuroblast differentiation	22140513	Process
2768677	GO:0016239	IMP	involved_in	positive regulation of macroautophagy	18794330	Process
2768677	GO:0035234	IMP	involved_in	ectopic germ cell programmed cell death	20838898	Process
2768677	GO:0040010	IMP	involved_in	positive regulation of growth rate	17686972	Process
2768677	GO:0040018	IMP	involved_in	positive regulation of multicellular organism growth	17686972	Process
2768677	GO:0042127	IMP	involved_in	regulation of cell population proliferation	21179433	Process
2768677	GO:0042246	IMP	involved_in	tissue regeneration	16920621	Process
2768677	GO:0042307	IMP	involved_in	positive regulation of protein import into nucleus	17686972	Process
2768677	GO:0042594	IMP	involved_in	response to starvation	25017064	Process
2768677	GO:0042771	IGI	involved_in	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	21205821	Process
2768677	GO:0042771	IMP	involved_in	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	10778860,12172011,12935877,16860746,25882045	Process
2768677	GO:0043553	IMP	involved_in	negative regulation of phosphatidylinositol 3-kinase activity	17686972	Process
2768677	GO:0043568	IMP	involved_in	positive regulation of insulin-like growth factor receptor signaling pathway	17686972	Process
2768677	GO:0045787	IGI	involved_in	positive regulation of cell cycle	16326395	Process
2768677	GO:0045893	IDA	involved_in	positive regulation of DNA-templated transcription	10778860	Process
2768677	GO:0045893	IMP	involved_in	positive regulation of DNA-templated transcription	17933869,24265704	Process
2768677	GO:0045944	IMP	involved_in	positive regulation of transcription by RNA polymerase II	12172011,17686972	Process
2768677	GO:0046533	IMP	involved_in	negative regulation of photoreceptor cell differentiation	19960025	Process
2768677	GO:0046620	IMP	involved_in	regulation of organ growth	21179433	Process
2768677	GO:0048477	IGI	involved_in	oogenesis	20522776	Process
2768677	GO:0060785	IMP	involved_in	regulation of apoptosis involved in tissue homeostasis	25882045	Process
2768677	GO:0071480	IMP	involved_in	cellular response to gamma radiation	12172011,24265704,26996664	Process
2768677	GO:0072332	IMP	involved_in	intrinsic apoptotic signaling pathway by p53 class mediator	12172011	Process
2768677	GO:2000685	IMP	involved_in	positive regulation of cellular response to X-ray	14729967	Process