Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 2902
  • Symbol: GRIN1
  • Description: glutamate ionotropic receptor NMDA type subunit 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2902 GO:0004972 IDA contributes_to NMDA glutamate receptor activity 7679115,7685113 Function
2902 GO:0004972 IDA enables NMDA glutamate receptor activity 26919761,28105280 Function
2902 GO:0004972 IMP enables NMDA glutamate receptor activity 28228639 Function
2902 GO:0005262 IDA contributes_to calcium channel activity 7685113 Function
2902 GO:0005515 IPI enables protein binding 17047094,17997397,32814053 Function
2902 GO:0016594 IDA enables glycine binding 7685113,28105280 Function
2902 GO:0016594 IMP enables glycine binding 17047094 Function
2902 GO:0016595 IDA enables glutamate binding 7685113 Function
2902 GO:0022849 IDA enables glutamate-gated calcium ion channel activity 26875626 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2902 GO:0005886 IDA located_in plasma membrane 7685113,26875626,26919761,28105280,28228639 Component
2902 GO:0017146 IDA part_of NMDA selective glutamate receptor complex 7679115,10480938,17047094,26875626,26919761,28105280..... Component
2902 GO:0030425 IDA located_in dendrite 10749211 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
2902 GO:0006812 IDA involved_in monoatomic cation transport 7685113 Process
2902 GO:0035235 IMP involved_in ionotropic glutamate receptor signaling pathway 28228639 Process
2902 GO:0042391 IDA involved_in regulation of membrane potential 7679115,7685113,17047094 Process
2902 GO:0045471 IDA involved_in response to ethanol 18445116 Process
2902 GO:0097553 IDA involved_in calcium ion transmembrane import into cytosol 26875626 Process
2902 GO:1904646 IGI NOT involved_in cellular response to amyloid-beta 21883149 Process
2902 GO:1905429 IDA involved_in response to glycine 28105280 Process