Gene Ontology

Gene Info

  • Species: Rat (Rattus norvegicus)
  • GeneID: 29386
  • Symbol: Mecp2
  • Description: methyl CpG binding protein 2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
29386 GO:0000122 IDA involved_in negative regulation of transcription by RNA polymerase II 9038338 Process
29386 GO:0000122 IMP involved_in negative regulation of transcription by RNA polymerase II 24636259 Process
29386 GO:0007507 IEP involved_in heart development 20735989 Process
29386 GO:0010212 IEP involved_in response to ionizing radiation 17148264 Process
29386 GO:0010288 IEP involved_in response to lead ion 23246732 Process
29386 GO:0010628 IMP involved_in positive regulation of gene expression 24636259 Process
29386 GO:0010629 IMP involved_in negative regulation of gene expression 19217433 Process
29386 GO:0014003 IEP involved_in oligodendrocyte development 26140854 Process
29386 GO:0014070 IEP involved_in response to organic cyclic compound 22109888 Process
29386 GO:0021510 IEP involved_in spinal cord development 12605461 Process
29386 GO:0021549 IEP involved_in cerebellum development 14751287 Process
29386 GO:0021740 IEP involved_in principal sensory nucleus of trigeminal nerve development 12605461 Process
29386 GO:0021756 IEP involved_in striatum development 12605461 Process
29386 GO:0021766 IEP involved_in hippocampus development 14751287 Process
29386 GO:0021772 IEP involved_in olfactory bulb development 12605461 Process
29386 GO:0021794 IEP involved_in thalamus development 12605461 Process
29386 GO:0021987 IEP involved_in cerebral cortex development 14751287 Process
29386 GO:0030182 IEP involved_in neuron differentiation 12605461 Process
29386 GO:0031915 IMP involved_in positive regulation of synaptic plasticity 23015442 Process
29386 GO:0032091 IMP involved_in negative regulation of protein binding 24636259 Process
29386 GO:0032355 IEP involved_in response to estradiol 22109888 Process
29386 GO:0035176 IMP involved_in social behavior 18614683,27313794 Process
29386 GO:0035865 IDA involved_in cellular response to potassium ion 14593183 Process
29386 GO:0042220 IDA involved_in response to cocaine 23688924 Process
29386 GO:0042220 IEP involved_in response to cocaine 20711185 Process
29386 GO:0044030 IEP involved_in regulation of DNA methylation 20735989 Process
29386 GO:0044030 IMP involved_in regulation of DNA methylation 20735989 Process
29386 GO:0045892 IDA involved_in negative regulation of DNA-templated transcription 9038338 Process
29386 GO:0048286 IEP involved_in lung alveolus development 21425435 Process
29386 GO:0048709 IEP involved_in oligodendrocyte differentiation 20697302 Process
29386 GO:0048712 IDA involved_in negative regulation of astrocyte differentiation 16881068 Process
29386 GO:0050807 IDA involved_in regulation of synapse organization 19442733 Process
29386 GO:0050807 IMP involved_in regulation of synapse organization 19442733 Process
29386 GO:0060999 IMP involved_in positive regulation of dendritic spine development 24188180 Process
29386 GO:0061000 IMP involved_in negative regulation of dendritic spine development 24636259 Process
29386 GO:0071317 IDA involved_in cellular response to isoquinoline alkaloid 22262897 Process
29386 GO:0090327 IMP involved_in negative regulation of locomotion involved in locomotory behavior 27313794 Process
29386 GO:0099611 IMP involved_in regulation of action potential firing threshold 27313794 Process
29386 GO:1901953 IMP involved_in positive regulation of anterograde dense core granule transport 22127389 Process
29386 GO:1901956 IMP involved_in positive regulation of retrograde dense core granule transport 22127389 Process
29386 GO:1903860 IMP involved_in negative regulation of dendrite extension 24636259 Process
29386 GO:1903861 IMP involved_in positive regulation of dendrite extension 19442733 Process
29386 GO:1903941 IMP involved_in negative regulation of respiratory gaseous exchange 27313794 Process
29386 GO:1905492 IMP involved_in positive regulation of branching morphogenesis of a nerve 19442733 Process
29386 GO:2000635 IMP involved_in negative regulation of primary miRNA processing 24636259 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
29386 GO:0000400 IDA enables four-way junction DNA binding 16314321 Function
29386 GO:0003682 IDA enables chromatin binding 23688924 Function
29386 GO:0005515 IPI enables protein binding 17296936,21070191 Function
29386 GO:0008327 IDA enables methyl-CpG binding 12473678 Function
29386 GO:0010385 IDA enables double-stranded methylated DNA binding 9038338,16314321 Function
29386 GO:0019899 IPI enables enzyme binding 12473678 Function
29386 GO:0019904 IPI enables protein domain specific binding 24636259 Function
29386 GO:0031490 IDA enables chromatin DNA binding 9038338 Function
29386 GO:0042826 IPI enables histone deacetylase binding 23671328,24441681 Function
29386 GO:0045322 IDA enables unmethylated CpG binding 16314321 Function
29386 GO:1990841 IDA enables promoter-specific chromatin binding 21425435 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
29386 GO:0000785 IDA part_of chromatin 9038338 Component
29386 GO:0032991 IDA part_of protein-containing complex 12473678,21070191 Component
29386 GO:0098978 IDA is_active_in glutamatergic synapse 19442733 Component
29386 GO:0098978 IMP is_active_in glutamatergic synapse 19442733 Component